Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-667-5 | CAS number: 98-42-0
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- other: WOE
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- other: conclusion of WoE Study
- Title:
- Weight of evidence for skin irritation from MSDS for CAS No.: 98-42-0
- Author:
- TCI America
- Year:
- 2 012
- Bibliographic source:
- Material safety data sheet - TCI America Portland OR
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Material safety data sheet - TCI America Portland OR
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-amino-4-methoxybenzenesulphonic acid
- EC Number:
- 202-667-5
- EC Name:
- 3-amino-4-methoxybenzenesulphonic acid
- Cas Number:
- 98-42-0
- Molecular formula:
- C7H9NO4S
- IUPAC Name:
- 3-amino-4-methoxybenzenesulphonic acid
- Details on test material:
- - Name of test material: 3-amino-4-methoxybenzenesulphonic acid
- Molecular formula: C7H9NO4S
- Molecular weight: 203.22
- Substance type: organic
- Physical state: Soild
Constituent 1
Test animals
- Strain:
- not specified
Test system
- Type of coverage:
- other: unspecified
- Preparation of test site:
- other: unspecified
- Vehicle:
- unchanged (no vehicle)
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Reversibility:
- other: unspecified
- Remarks on result:
- other: positive
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (corrosive)
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- 3-amino-4-methoxybenzenesulphonic acid is estimated to be corrosive to skin.
- Executive summary:
3-amino-4-methoxybenzenesulphonic acid is observed to be corrosive to skin. Skin contact may produce burns as the pH of the substance indicates that the chemical is acidic in nature. Moreover the analog for the target substance (which have more than 90% similarity) also indicates corrosive characteristics on skin and eye. Thus, based on these evidences it can be infered that the target, 3-amino-4-methoxybenzenesulphonic acid, will be corrosive to skin and so will qualify for classification in category 1
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
