Registration Dossier
Registration Dossier
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EC number: 700-081-9 | CAS number: 635708-74-6
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Remarks:
- other: QSAR : Derek for Windovs
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: No test data - QSAR data
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: software
- Title:
- Unnamed
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Knowledge base of Derek for Windovs QSAR
- Principles of method if other than guideline:
- Rulebases - they consist of descriptions of molecular substructures (structural alerts), which have been associated with toxic endpoints on the basis of existing knowledge.
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- As a substance for QSAR evaluation - main component was used.
Constituent 1
Results and discussion
In vivo
Results
- Irritation parameter:
- other: Derek ranking
- Basis:
- other: softvare calculation
- Remarks on result:
- other: PLAUSIBLE
- Irritant / corrosive response data:
- Derek for Windovs Irritation of the eye - PLAUSIBLE - Alert 227 Allyl halide
Any other information on results incl. tables
Endpoint evaluated according QSAR (Derek for Windows) ranking and calculation.
Applicant's summary and conclusion
- Interpretation of results:
- irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: other: Results of QSAR
- Conclusions:
- Substance is eye irritating.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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