Registration Dossier
Registration Dossier
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EC number: 942-063-5 | CAS number: -
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16.12.2013 to 10.01.2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Siemens AG, Prozess-Sicherheit, Industriepark Höchst, B 596 & B 598, D-65926 Frankfurt am Main, Germany
- Type of method:
- flask method
Test material
- Reference substance name:
- Fatty acids, coco derivs. II, reaction products with glycine, potassium salts
- EC Number:
- 942-063-5
- Molecular formula:
- R-CO-NH-CH2-COOK (Note: "R-CO-" is a fatty acid residue)
- IUPAC Name:
- Fatty acids, coco derivs. II, reaction products with glycine, potassium salts
- Test material form:
- solid
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Ajinomoto Co., Inc., 15-1 Kyobashi 1-Chome, Chuo-Ku, Tokyo 1048315, Japan/Batch No.: 130808
- Expiration date of the lot/batch: 07.08.2016
- Purity test date: 24.09.2013
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature (10-30°C)
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing:no
FORM AS APPLIED IN THE TEST (if different from that of starting material): solid
Results and discussion
Water solubility
- Key result
- Water solubility:
- 311 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Loading of aqueous phase:
- 452 g/L
- Incubation duration:
- <= 72 h
- Temp.:
- 20 °C
- pH:
- 9
Applicant's summary and conclusion
- Conclusions:
- The water solubility was determined to be 311 g/L at 20°C.
- Executive summary:
The water solubility of acylglycinate GCK-12H -T (dry matter) was investigated in a study conducted according EU Method A.6 (Water Solubility) and OECD Guideline 105 (Water Solubility) and using the flask-method. The water solubility determined via HPLC measurements was found to be 311 g/L at 20°C. The recovery experiments with standard solutions indicated a sufficient accuracy of the analytical method.
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