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Diss Factsheets
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EC number: 809-852-5 | CAS number: 3395-98-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP Guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 3-ethenyl-5-methyl-1,3-oxazolidin-2-one
- EC Number:
- 809-852-5
- Cas Number:
- 3395-98-0
- Molecular formula:
- C6H9NO2
- IUPAC Name:
- 3-ethenyl-5-methyl-1,3-oxazolidin-2-one
- Details on test material:
- - Name of test material (as cited in study report): 5-Methyl-3-vinyloxazolidin-2-one
- Analytical purity: 99.5 area % (GC-area-%)
- Lot/batch No.: DEIMLIB-00070
Constituent 1
Study design
- Analytical monitoring:
- yes
- Buffers:
- - pH: 4, 7, 9
- Composition of buffer: pH 4 (Bernd Kraft; citric acid, sodium chloride, sodium hydroxide), pH 7 (Bernd Kraft; phosphate mixture), pH 9 (Bernd Kraft; boric acid, sodium hydroxide, potassium chloride), acetonitrile (Fluka), pH=4.008 (Bernd Kraft), pH=9.184 (Bernd Kraft)
Results and discussion
- Transformation products:
- yes
Identity of transformation productsopen allclose all
- No.:
- #2
Reference
- Reference substance name:
- Unnamed
- IUPAC name:
- Methyl alcohol
- Inventory number:
- InventoryMultipleMappingImpl [inventoryEntryValue=EC 200-659-6]
- CAS number:
- 67-56-1
- Molecular formula:
- CH4O
- Molecular weight:
- 32.042
- SMILES notation:
- CO
- InChl:
- InChI=1/CH4O/c1-2/h2H,1H3
- Details on hydrolysis and appearance of transformation product(s):
- The reaction of the test item with water under neutral or acidic conditions is well known. No hydrolysis products could be observed in any test (pH 4, pH 7 and pH 9) under the analytical conditions applied. The results which were calculated out of measurements at 20°C for pH 4 and pH 7 are similar to the calculated values from using the Arrhenius data.
Dissipation DT50 of parent compoundopen allclose all
- pH:
- 4
- Temp.:
- 20 °C
- DT50:
- 28.8 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: Half-lives measured
- pH:
- 4
- Temp.:
- 50 °C
- DT50:
- 1.5 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: Half.lives measured
- pH:
- 4
- Temp.:
- 60 °C
- DT50:
- 0.7 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: Half-lives measured
- pH:
- 7
- Temp.:
- 20 °C
- DT50:
- 1 952 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: Half-lives measured
- pH:
- 7
- Temp.:
- 50 °C
- DT50:
- 99.1 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: Half-lives measured
- pH:
- 7
- Temp.:
- 60 °C
- DT50:
- 42.4 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: Half-lives measured
- pH:
- 7
- Temp.:
- 70 °C
- DT50:
- 21.1 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: Half-lives measured
- pH:
- 9
- Temp.:
- 50 °C
- Remarks on result:
- other: no hydrolysis could be observed (<10% in 5 days)
Any other information on results incl. tables
Half-lives at 20°C and 25°C, calculated from the measured values:
pH value | Temperature | t1/2 |
pH 4 | 20°C | 24.0 h |
pH 4 | 25°C | 14.6 h |
pH 7 | 20°C | 1446.2 h |
pH 7 | 25°C | 888.3 h |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
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