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Diss Factsheets
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EC number: 930-985-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 1991-06-25 to 1991-08-22
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- - Name of test material (as cited in study report): Wessalith P, Natrium-Aluminium silikat
- Framework: monoclinic
- Related CAS number: 1318-02-1
- Physical state: white flocky powder
- Analytical purity: 80.6% active ingredient, 19.4% crystal water (79.8% active ingredient, source Degussa, respectively - two information sheets are given in the study, both supplied by the sponsor)
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- For preparing the test solutions 1000, 1800, 3200, 5600 and 10000 mg/L Wessalith P were weighed out and added to 1 L dilution water. The suspensions were stirred at 20°C for 1 h and then filtered through a paper filter (S&S 595 1/2).
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- ca. 24 h old, cultured in the laboratory according to guideline NPR, Nederlandse Praktijkrichtlijn, 6503
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 24 h
Test conditions
- Hardness:
- 204 mg/L expressed as CaCO3
- Test temperature:
- 20 +/- 1°C
- pH:
- 8.0-8.2
- Dissolved oxygen:
- > 7.0 mg/L
- Details on test conditions:
- Daphnids were exposed for 24 hours to a series of solutions of Wessalith P in 150 mL vessels each containing 100 mL test suspension or control medium (5 daphnids per vessel; four test vessels per test suspension or control; no aeration, no feeding).
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 2 808 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC100
- Effect conc.:
- 5 600 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 800 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- behaviour
Any other information on results incl. tables
The initial
pH value of the control and test solutions was determined to be 8.2
(control), 8.2, 9.1, 9.6, 9.9, 10.2 and 10.5 (highest concentration).
The measured pH after 24 h was reported as 8.0 (control), 8.0, 8.6, 9.0,
9.4, 9.6 and 9.8 (highest concentration).
Observations on the test solution: At the start of the test, all
suspensions were slightly turbid, turbidity increased with dosed amount.
After 24 h all aqueous phases were clear, but undissolving material was
sticking on the bottom of the test vessels.
The EC50 for mobility after 24 h was calculated as 2808 mg/L, EC100 5600
mg/L and NOEC 1800 mg/L. The NOEC for condition of the daphnids
(swimming behavior: slower movements, irregular movements) was
determined as 1000 mg/L.
During the study, a series of previous or further experiments were
performed:
- Pre-test with nominal concentrations between 56 and 1000 mg/L (spaced
by a factor of 1.8) plus 10000 mg/L. Only the highest treatment showed
an effect of the test substance on mobility and swimming behavior of
daphnids.
- Unfiltered versus filtered test suspensions in a limit test (1000 and
10000 mg/L): This test was carried out because it was shown in the first
test that the daphnids were physically hampered by undissolved material.
Unfiltered test suspensions resulted in increased immobilization and
affected swimming behavior of daphnids compared to filtered suspensions
(for the highest concentration of 10000 mg/L).
- Main test (results see above)
- ph test: dilution water adjusted to various high pH values because it
was likely that the mobility of daphnids in the tests with Wessalith P
was affected by the rather high pH values of the test suspensions. After
24 h, pH values of 10.5 and 11.0 and after 48 h, additionally pH 10.0
resulted in an increased immobility. Besides, swimming behavior was
affected in the respective treatments, and animals were paler than
control animals.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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