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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 483-990-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- read-across based on grouping of substances (category approach)
- Remarks:
- APP category
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Category is coherent for more than 10 endpoints. Ecotoxicological effect is non specific, linked to surfactant properties and no functional groups are present that may be associated with known specific ecotoxicity.
- Justification for type of information:
- Discussed in the document attached
Cross-reference
- Reason / purpose for cross-reference:
- read-across source
Reference
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: No deviation from OECD-202 guideline, GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Vehicle:
- no
- Test organisms (species):
- Daphnia magna
- Test type:
- static
- Water media type:
- freshwater
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 12 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- other: Dissolved Organic Carbon
- Basis for effect:
- mobility
- Validity criteria fulfilled:
- yes
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
Test guideline
- Version / remarks:
- Guidance on information requirements and chemical safety assessment - Chapter R.6: QSARs and
grouping of chemicals - ECHA, May 2008
- Principles of method if other than guideline:
- Guidance on information requirements and chemical safety assessment - Chapter R.6: QSARs and
grouping of chemicals - ECHA, May 2008 - GLP compliance:
- no
Test material
- Reference substance name:
- D-xylofuranose oligomeric dodecyl glycosides (degree of polymerisation = 1)
- Molecular formula:
- C15H30O5
- IUPAC Name:
- D-xylofuranose oligomeric dodecyl glycosides (degree of polymerisation = 1)
- Reference substance name:
- D-xylofuranose oligomeric dodecyl glycosides, degree of polymerisation 2
- Molecular formula:
- C20H38O9
- IUPAC Name:
- D-xylofuranose oligomeric dodecyl glycosides, degree of polymerisation 2
- Reference substance name:
- D-xylofuranose oligomeric tetradecyl glycosides (degree of polymerisation = 1)
- Molecular formula:
- C17H34O5
- IUPAC Name:
- D-xylofuranose oligomeric tetradecyl glycosides (degree of polymerisation = 1)
- Reference substance name:
- D-xylofuranose oligomeric tetradecyl glycosides, degree of polymerisation 2
- Molecular formula:
- C20H38O9
- IUPAC Name:
- D-xylofuranose oligomeric tetradecyl glycosides, degree of polymerisation 2
- Reference substance name:
- D-glucopyranose oligomeric dodecyl glycosides, degree of polymerisation 1
- Molecular formula:
- C15H30O5
- IUPAC Name:
- D-glucopyranose oligomeric dodecyl glycosides, degree of polymerisation 1
- Reference substance name:
- D-glucopyranose oligomeric dodecyl glycosides, degree of polymerisation 2
- Molecular formula:
- C20H39O9
- IUPAC Name:
- D-glucopyranose oligomeric dodecyl glycosides, degree of polymerisation 2
- Reference substance name:
- D-glucopyranose oligomeric tetradecyl glycosides, degree of polymerisation 1
- Molecular formula:
- C15H30O5
- IUPAC Name:
- D-glucopyranose oligomeric tetradecyl glycosides, degree of polymerisation 1
- Reference substance name:
- D-glucopyranose oligomeric tetradecyl glycosides, degree of polymerisation 2
- Molecular formula:
- C20H38O9
- IUPAC Name:
- D-glucopyranose oligomeric tetradecyl glycosides, degree of polymerisation 2
- Reference substance name:
- Glucose
- EC Number:
- 200-075-1
- EC Name:
- Glucose
- Cas Number:
- 50-99-7
- Molecular formula:
- C6H12O6
- IUPAC Name:
- D-glucose
- Reference substance name:
- Xylose
- EC Number:
- 200-400-7
- EC Name:
- Xylose
- Cas Number:
- 58-86-6
- Molecular formula:
- C5H10O5
- IUPAC Name:
- Oxane-2,3,4,5-tetrol (D)
- Reference substance name:
- Tetradecanol
- EC Number:
- 204-000-3
- EC Name:
- Tetradecanol
- Cas Number:
- 112-72-1
- Molecular formula:
- C14H30O
- IUPAC Name:
- Tetradecan-1-ol
- Reference substance name:
- Dodecan-1-ol
- EC Number:
- 203-982-0
- EC Name:
- Dodecan-1-ol
- Cas Number:
- 112-53-8
- Molecular formula:
- C12H26O
- IUPAC Name:
- Dodecan-1-ol
Constituent 1
Constituent 2
Constituent 3
Constituent 4
Constituent 5
Constituent 6
Constituent 7
Constituent 8
Constituent 9
Constituent 10
Constituent 11
Constituent 12
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 7 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Daphnia 48h-EC50 for APP-6726 is 7.00 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.