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Diss Factsheets
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EC number: 457-900-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 23 May - 21 Jun 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP - Guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Qualifier:
- according to guideline
- Guideline:
- ISO DIS 9439 (Ultimate Aerobic Biodegradability - Method by Analysis of Released Carbon Dioxide)
- GLP compliance:
- yes
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): PM-5927
- Physical state: off-white powder
- Lot/batch No.: 07-02
- Expiration date of the lot/batch: 05 Feb 2008
- Storage condition of test material: at room temperature in the dark
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Municipal sewage treatment plant: ‘Waterschap de Maaskant’, ‘s-Hertogenbosch, The Netherlands
- The sludge was kept under continuous aeration until further treatment.
- Preparation of inoculum for exposure: Before use, the sludge was allowed to settle for 73 min and the liquid decanted for use as inoculum at the amount of 20 mL/L of mineral medium.
- The concentration of suspended solids was 2.5 g/L in the concentrated sludge. - Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 21 mg/L
- Based on:
- test mat.
- Initial conc.:
- 12 mg/L
- Based on:
- other: TOC
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Mineral medium
- Test temperature: 20.6 - 21.7 °C
- pH: 7.5 - 7.7
- Aeration of dilution water: The mixture of mineral components, Milli-RO water (ca. 80% total volume) and inoculum (1% final volume) was aerated with synthetic air overnight to purge the system of CO2.
- Suspended solids concentration: 2.5 g/L
- other: The test media were continuously aerated and stirred during the test. Preparation of the test solutions was as much as possible performed under yellow light.
TEST SYSTEM
- Culturing apparatus: 2 litre all-glass brown coloured bottles
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: CO2-free air was sparged through the scrubbing solutions at a constant rate.
- Details of trap for CO2: A mixture of oxygen (21%) and nitrogen (79%) was passed through a bottle, containing 0.5 – 1 L 0.0125 M Ba(OH)2 solution. The CO2 produced in each test bottle reacted with the barium hydroxide in the gas scrubbing bottle and precipitated out as barium carbonate.
SAMPLING
- Sampling frequency: on day 2, 5, 7, 9, 14, 19, 23, 27, 29
- Sampling method: The amount of CO2 produced was determined by titrating the remaining Ba(OH)2 with 0.05 M standardized HCL. On the 28th day, the pH of the test suspensions was measured and 1 mL of concentrated HCL was added to each bottle. The bottles were aerated overnight to drive off CO2 present in the test suspension. The final titration was made on day 29.
CONTROL AND BLANK SYSTEM
- Inoculum blank: 2 replicates
- Positive control: 1 replicate
- Toxicity control: 1 replicate
Reference substance
- Reference substance:
- acetic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 5.5
- Sampling time:
- 29 d
BOD5 / COD results
- Results with reference substance:
- Degradation: 64% after 14 days, 60% pass level was reached.
Any other information on results incl. tables
Table 1: Percentage biodegradation of test substance, reference substance and toxicity control
Day |
Test substance (% degradation) |
Reference substance (% degradation) |
Toxicity control (% degradation) |
||
Replicate 1 |
Replicate 2 |
Ø |
|||
2 |
0 |
1 |
1 |
2 |
0 |
5 |
1 |
2 |
1 |
35 |
13 |
7 |
1 |
2 |
2 |
49 |
20 |
9 |
2 |
3 |
2 |
57 |
24 |
14 |
2 |
3 |
3 |
64 |
28 |
19 |
4 |
3 |
3 |
68 |
31 |
23 |
5 |
3 |
4 |
71 |
33 |
27 |
6 |
3 |
5 |
74 |
34 |
29 |
6 |
3 |
5 |
76 |
34 |
29 |
7 |
3 |
5 |
76 |
35 |
29 |
8 |
3 |
5* |
77 |
35 |
* value as stated in report, actual mean = 5.5
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- CLP: Aquatic chronic 2, H411 (basis for classification: not rapidly biodegradable and a NOEC (growth rate) of 0.22 mg/L for algae)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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