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Diss Factsheets
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EC number: 439-840-1 | CAS number: 20846-91-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
In a GLP study conducted according to OECD Guideline 203, trisodium EDDS was not acutely toxic to the freshwater fish, Brachydanio rerio, when tested up to a nominal concentration of 1000 mg/L, therefore the 96-h NOEC value for survival and condition was 1000 mg/L.
Key value for chemical safety assessment
Additional information
A GLP study conducted according to OECD Guideline 203 was performed to determine the acute toxicity of trisodium EDDS to Brachydanio rerio (10 fish/concentration). The test was carried out under semi-static conditions with daily replacement of the test solutions. Fish were exposed to trisodium EDDS in freshwater at nominal concentrations of 0, 100, 180, 320, 560 and 1000 mg/L and observed for survival, condition (swimming behaviour, colour, respiratory function or any other visually observable morphological or behavioural criterion) of the survivors after 24, 48, 72 and 96 h of exposure. After 96 h, all animals were alive and their condition was comparable to that of the control animals. All test solutions were completely clear (visually assessed) throughout the test. In conclusion, the 96-h NOEC for survival and condition of freshwater fish was 1000 mg/L (the highest tested nominal concentration), and the 96-h LC50 would be >1000 mg/L (Hooftman and van Drongelen-Sevenhuijsen, 1993).
No data in marine fish are currently available for EDDS acid or its trisodium salt.
[Data on trisodium EDDS is considered relevant to use for understanding the potential toxicity to fish of EDDS acid, and is acceptable for using as read-across information].
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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