Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 267-510-5 | CAS number: 67874-81-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Abiotic degradation:
Air:
No experimental data on the phototransformation of the substance in air are available. Based on estimation with the QSAR model AopWin (v1.92), in air the substance undergoes rapid degradation after reaction with hydroxyl radicals. The DT50 -value after reaction with hydroxyl radicals is 0.54 days. This indicates that the substance is not a long-range transported chemical in air according to the UNECE criteria (http://www.unece.org/fileadmin/DAM/env/documents/2000/ece/eb/ece%20eb%20air.60.e.pdf). This halflife will not be used for the CSA because these are calculated and not experimental values.
Water:
The hydrolysis test for Cedramber is not needed because of its ready biodegradability. The substance is expected to be hydrolytically stable because it does not contain hydrolysable groups such as ester, carbamates, epoxides, halomethanes, acylhalides (see Hydrowin, EpiSuite for all hydrolysable groups). The half-life at 25°C is > 1 year.
Biodegradability:
The ready biodegradability of Cedramber was investigated in a study conducted in accordance with OECD TG 301D (Closed Bottle Test). The concentration tested was 2 mg/l test substance. The biodegradability of the substance was with river water 60% at day 28. This biodegradation percentage at day 28 allows classification as readily biodegradable. The 14 -day time window should not be applied because this substance contains many small impurities. A slight inhibition of the endogenous respiration of the microorganisms present in river water at day 7 by the test substance was detected.
Bioaccumulation:
Bioaccumulation in aquatic species is based on the available information (log Kow and calculated BCF values) and is deemed sufficient to take into account as a worst case value for the chemical safety assessment.The BCFs for aquatic and terrestrial organisms were calculated using QSARs of Veith et al. (1979) and Jager (1998), both incorporated in the EUSES model, and yielded values of 4320 and 1510 L/kg ww, respectively.
Transport and distribution
Using the HPLC estimation method based on soil-adsorption-reference data, the log Koc for Cedramber has been determined as 4.5 (Koc= 30000). The study was performed in accordance with EC C.9 and OECD 121 and in compliance with GLP.
Distribution modelling:
Based on Level III environmental distribution modelling using EPISUITE (assuming equal and continuous releases to air, water and soil) using the CAS number 67874-81-1 it is estimated that the majority of the substance released to the environment will partition mainly into soil (87.5%) and water (8.0%) with minor amounts to sediment air (4.0%) and air (0.5%).
The SimpleTreat model, which is incorporated in EUSES, simulates the distribution of the substance in a Sewage Treatment Plant.Model calculations show that 33.2% of the substance will be degraded and that 58.9%, 6.57% and 1.38% will partition to sewage sludge, water and air, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.