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EC number: 239-914-1 | CAS number: 15816-71-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993-01-27 - 1993-03-03
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.3 (Algal Inhibition test)
- Deviations:
- not specified
- GLP compliance:
- no
- Analytical monitoring:
- yes
- Vehicle:
- no
- Details on test solutions:
- Test concentrations: 0.008, 0.016, 0.031, 0.063, 0.125, 0.25, 0.5, 1 mg/l
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
- pH:
- 10.3 - 10.4
- Nominal and measured concentrations:
- Nominal test concentrations: 0.008, 0.016, 0.031, 0.063, 0.125, 0.25, 0.5, 1 mg/l
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Key result
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.016 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Key result
- Duration:
- 72 h
- Dose descriptor:
- LOEC
- Effect conc.:
- 0.031 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Validity criteria fulfilled:
- yes
- Conclusions:
- The toxicity towards aquatic algae of dicyclohexylamine was evaluated according to EU method C.3. The NOEC for inhibition of specific growth rate after 72 hours was 0.016 mg/l. The EC50 was estimated as > 1mg/l.
- Executive summary:
The toxicity towards aquatic algae of dicyclohexylamine was evaluated according to EU method C.3. The NOEC for inhibition of specific growth rate after 72 hours was 0.016 mg/l. The EC50 was estimated as > 1mg/l.
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- other: CLH-Report
- Adequacy of study:
- key study
- Study period:
- 2013-06-06
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Vehicle:
- not specified
- Test organisms (species):
- Scenedesmus sp.
- Test type:
- static
- Water media type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 72 h
- Hardness:
- not specified
- Test temperature:
- not specified
- pH:
- not specified
- Dissolved oxygen:
- not specified
- Salinity:
- not specified
- Conductivity:
- not specified
- Nominal and measured concentrations:
- not specified
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1.67 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: results given for octanoic acid on equimolar basis
- Key result
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.47 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: results given for octanoic acid on equimolar basis
- Validity criteria fulfilled:
- yes
- Conclusions:
- The toxicity of the read across substance decanoic acid towards Scenedesmus subspicatus was determined according to OECD 201. The calculated ErC50 was 2 mg/L (results given in Octanoic acid on equimolare basis: 1.67 mg/L Octanoic acid).
- Executive summary:
The toxicity of the read across substance decanoic acid towards Scenedesmus subspicatus was determined according to OECD 201. The calculated ErC50 was 2 mg/L ( result given in Octanoic acid on equimolare basis: 1.67 mg/L Octanoic acid).
Referenceopen allclose all
Description of key information
Since the substance to be registered is Octanoic acid, compound with dicyclohexylamine (1:1) which will dissociate to 1 mol octanoic acid and 1 mol dicyclohexylamine, the lowest EC50 of 1 mg/l and the lowest NOEC of 0.016 mg/l for DCHA acid is calculated for the entire substance considering the molar mass of 325.5 g/mol (55.7% DCHA).
Therefore the EC50 for aquatic algae for Octanoic acid, compound with dicyclohexylamine (1:1) is 1.8 mg/ml and the NOEC is 0.029 mg/l respectively.
DCHA:
The toxicity towards aquatic algae of dicyclohexylamine was evaluated according to EU method C.3. The NOEC for inhibition of specific growth rate after 72 hours was 0.016 mg/l. The EC50 was estimated as > 1mg/l.
Octanoic acid:
The toxicity of the read across substance decanoic acid towards Scenedesmus subspicatus was determined according to OECD 201. The calculated ErC50 was 2 mg/L (corresponding to 1.67 mg/L Octanoic acid).
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1.8 mg/L
- EC10 or NOEC for freshwater algae:
- 0.029 mg/L
Additional information
Read Across justification:
In aqueous systems Octanoic acid, compound with dicyclohexylamine (1:1) is hydrolytically very unstable so that in aqueous solution a rapid decomposition to the educts can be observed. The substance will rapidly dissociate to octanoic acid and dicyclohexylamine. Therefore Octanoic acid, compound with dicyclohexylamine (1:1) is not stable at “standard” testing conditions representative for human and environmental exposure. Hence, it is fully justified to apply the read-across methodology by use of the respective data from the breakdown/decomposition products to describe the (eco)toxicological behaviour of the substance to be registered.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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