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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 219-157-3 | CAS number: 2378-02-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Description of first aid measures
Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention.
Skin Contact: Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. Get medical attention.
Ingestion: Clean mouth with water. Get medical attention.
Inhalation: Remove from exposure, lie down. Remove to fresh air. If not breathing, give artificial respiration. Get medical attention.
Self-Protection of the First Aider: Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination.
Most important symptoms and effects, both acute and delayed
Difficulty in breathing. Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting
Indication of any immediate medical attention and special treatment needed
Notes to Physician: Treat symptomatically. Symptoms may be delayed.
Fire-fighting measures
Extinguishing media
Suitable Extinguishing Media: Water spray. Carbon dioxide (CO 2). Dry chemical. Chemical foam.
Extinguishing media which must not be used for safety reasons: No information available.
Special hazards arising from the substance or mixture
Thermal decomposition can lead to release of irritating gases and vapors.
Hazardous Combustion Products: Carbon monoxide (CO), Carbon dioxide (CO2), Gaseous hydrogen fluoride (HF).
Advice for firefighters
As in any fire, wear self-contained breathing apparatus pressure-demand and full protective gear.
Accidental release measures
Personal precautions, protective equipment and emergency procedures: Ensure adequate ventilation.
Environmental precautions: Keep in closed container at all times except of when intentionally in use and do not release to surface waters or soil.
Methods and material for containment and cleaning up: Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Keep in suitable, closed containers for disposal.
Handling and storage
Precautions for safe handling: Avoid contact with skin and eyes. Do not breathe mist/vapors/spray.
Hygiene Measures: Handle in accordance with good industrial hygiene and safety practice. Keep away from food, drink and animal feeding stuffs. Do not eat, drink or smoke when using this product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Wash hands before breaks and after work.
Conditions for safe storage, including any incompatibilities: Keep in a dry, cool and well-ventilated place. Keep container tightly closed.
Specific end use(s): Intermediate use and use in R&D laboratories
Transport information
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Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
Control parameters
Exposure limits: This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies.
Biological limit values: This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific regulatory bodies.
Exposure controls
Engineering Measures: Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source.
Personal protective equipment
Eye Protection: Goggles (European standard - EN 166)
Hand Protection: Protective gloves Skin and body protection (glove material e.g. Viton or similar, according to EN 374). Wear appropriate protective gloves and clothing to prevent skin exposure. Inspect gloves before use and observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion.
Respiratory Protection: No protective equipment is needed under normal use conditions.
Large scale/emergency use: Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Small scale/Laboratory use: Maintain adequate ventilation
Environmental exposure controls: No information available
Stability and reactivity
Reactivity: None known, based on information available
Chemical stability: Stable under normal conditions.
Possibility of hazardous reactions: Hazardous Polymerization No information available, but not expected.
Hazardous Reactions: No information available.
Conditions to avoid: Incompatible products.
Incompatible materials Strong oxidizing agents. Strong acids. Strong bases. Strong reducing agents.
Hazardous decomposition products: Carbon monoxide (CO). Carbon dioxide (CO2). Gaseous hydrogen fluoride (HF).
Disposal considerations
Waste treatment methods
Waste from Residues/Unused Products: Waste is classified as hazardous. Dispose of in accordance with the European Directives on waste and hazardous waste. Dispose of in accordance with local regulations.
Contaminated Packaging: Dispose of containers to hazardous or special waste collection point.
European Waste Catalogue (EWC): According to the European Waste Catalog, Waste Codes are not product specific, but application specific. Waste codes should be assigned by the user based on the application for which the product was used. Do not empty into drains.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.