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EC number: 217-157-8 | CAS number: 1758-73-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The test substance is unstable under alkaline conditions.
Key value for chemical safety assessment
Additional information
No experimental data according to accepted guidelines are
available for this endpoint. In accordance with Regulation (EC) No
1907/2006, Annex VIII, 9.2.2.1., column 2 testing is not required since
aminoiminomethanesulphinic acid (CAS No. 1758-73-2) is readily
biodegradable. However, data from literature indicate that the substance
is unstable under alkaline conditions. Miller et al. (1988) investigated
the stability of aminoiminomethanesulphinic acid in buffer solutions at
pH 7.4, pH 10 and pH 13-14 for 24 h. Urea and cyanamide were identified
as primary degradation products. After 24 h 5% formation of urea was
recorded at pH 7.4, whereas 35% formation of urea and 5% of cyanamide
was measured at pH 10. At pH 13 85% formation of urea was found.
Svarovsky et al. (2001) studied the kinetics and mechanism of
decomposition of thioureas in alkaline solutions. The decomposition of
thiourea dioxide is characterized by an induction period which is
followed by the formation of dithionite (S2O4 2-) under aerobic
conditions.The initial step of decomposition is the cleavage of the C-S
bond to give an urea residue and the sulfoxylate ion, SO2-, which is the
precursor to the formation of dithionite vial a rapid equilibrium. In
aerobic environments the sulfoxylate ion can produce the highly
tissue-damaging series of reactive oxygen species superoxide, peroxide,
and hydroxyl radical. These species could be responsible for the
inherent toxicities associated with thioureas.
An additional study which is available only as a short summary,
indicated that an aqueous solution of aminoiminomethanesulphinic acid is
unstable under aerobic conditions at 20 °C (OECD, 2002). 30% of the
substance were degraded after 22 h.
All available data indicate that aminoiminomethanesulphinic acid is
unstable under alkaline conditions leading to the formation of urea.
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