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EC number: 217-110-1 | CAS number: 1742-95-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The predicted data from QSAR model suggests the Inhibition growth concentration (IGC50) for the test substance 4-aminonaphthalene-1,8-dicarboximide was estimated to be 356.234008789 mg/L on Tetrahymena pyriformis on the basis of growth inhibition effect.
Key value for chemical safety assessment
Additional information
Predicted model data and experimental study result for the test chemical 4-aminonaphthalene-1,8-dicarboximide (CAS No. 1742-95-6) with respective read across were reviewed to summarize the following information:
In key study the 48 hrs aquatic toxicity study was predicted to assess toxic effects of the test compound 4-aminonaphthalene-1,8-dicarboximide (CAS No. 1742-95-6)and the result were predicted (SSS QSAR Prediction model, 2016). The study was based on the effects of the test compound on Tetrahymena pyriformis (Bacteria) in a static fresh water system. The predicted data suggests the Inhibition growth concentration (IGC50) for the test compound was estimated to be 356.234008789 mg/l on the basis of growth inhibition effect.
Above predicted inhibition concentration for target chemical supported by experimental study for read across chemical Phthalimide (Cas no. 85-41-6) which is indicates that effect concentration i.e EC0 on the basis of inhibition of cell inhibition for 16 hrs. was found to be 260 mg/l. (SIDS INITIAL ASSESSMENT PROFILE;2005 and INERIS database,2005)
Thus, based on above all effect values, it can be concluded that the target chemical 4-aminonaphthalene-1,8-dicarboximide (CAS No. 1742-95-6) can be considered as non-toxic to micro organisms.
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