Registration Dossier
Registration Dossier
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EC number: 212-052-3 | CAS number: 756-79-6
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Additional information
Decreased conception rate and effects on male genitals, etc. have been reported in reproductive ability tests in rats and mice (NTP TR 33223, Dunnick 1984). The dominant lethal action is observed also in germ-cell mutagenicity (Dunnick 1984).
Short description of key information:
The substance caused adverse effects on fertility in male rats. Experimental data for female animals is not available.
Effects on developmental toxicity
Additional information
Dangerous Substance Directive (67/548/EEC)
The available studies are considered reliable and suitable for classification purposes under 67/548/EEC in regard to fertility. As a result the substance is considered to be classified for reproductive toxicity (R62) under Directive 67/548/EEC, as amended for the 28th time in Directive 2001/59/EC.
Classification, Labelling, and Packaging Regulation (EC) No. 1272/2008
The available experimental test data are reliable and suitable for classification purposes under Regulation 1272/2008 in regard to fertility. As a result the substance is considered to be classified in Category 2 for reproductive toxicity under Regulation (EC) No. 1272/2008.
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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