Registration Dossier
Registration Dossier
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EC number: 212-052-3 | CAS number: 756-79-6
Endpoint summary
Administrative data
Description of key information
DMMP is of low acute oral toxicity after gavage application. LD50 values were reported to be higher than 5000 mg/kg bw in several reliable studies. It was also found to be of low acute dermal toxicity as tested with doses of 2000 mg/kg bw. No mortality was observed in an acute inhalation study at the dose of > 2589 mg/m³ air . All studies were performed in a design sufficiently similar or identical to the current OECD testing guideline.
Key value for chemical safety assessment
Additional information
Acute oral toxicity values were above 5000 mg/kg bw with the exception of two reports that were found in the US TSCA8e inventory by CAS-no search. The actual identifier in the reports do not allow assessment of the purity or composition of the test material. The fairly low LD50 values in the range of 1000 mg/kg bw is in contrast to all other well documented acute and repeated dose toxicity data. Therefore, the data is not taken into account for classification and labelling.
The following reports are concerned:
TSCATS (1992a). Report on oral LD50 in rats. CAP ID No. 8ECAP-0014, OTS 0540431. Testing laboratory: Cannon Laboratories, Inc., P. O. Box 3627, Reading, Pa. 19605. Report no.: 8E-2383. Owner company: Mobil Chemical Company. Study number: MTCR-129-78. Report date: 1978-08-24.
TSCATS (1992b). Report on oral LD50 in rats. CAP ID No. 8ECAP-0014, OTS 0540431. Testing laboratory: Cannon Laboratories, Inc., P. O. Box 3627, Reading, Pa. 19605. Report no.: 6E-9831. Owner company: Mobil Chemical Company. Study number: MTCR-93-76. Report date: 1976-12-10.
Justification for classification or non-classification
Dangerous Substance Directive (67/548/EEC)
The available studies are considered reliable and suitable for classification purposes under 67/548/EEC. As a result the substance is not considered to be classified for acute oral, dermal or inhalation toxicity under Directive 67/548/EEC, as amended for the 28th time in Directive 2001/59/EC.
Classification, Labelling, and Packaging Regulation (EC) No. 1272/2008
The available experimental test data are reliable and suitable for classification purposes under Regulation 1272/2008. As a result the substance is not considered to be classified for acute oral, dermal or inhalation toxicity under Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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