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Inventar tvari u skladu s Prilogom III.

Inventar tvari u skladu s Prilogom III.

ECHA je sastavila inventar tvari koje vjerojatno ispunjavaju kriterije iz Priloga III. Uredbi REACH. Njegova je svrha pomoći podnositeljima registracije da utvrde moraju li ispuniti smanjene zahtjeve za dostavu minimalnih informacija ili dostaviti potpuni skup informacija iz Priloga VII.

Inventar je sastavljen uz pomoć javno dostupnih baza eksperimentalnih podataka i na temelju rezultata dobivenih primjenom modela (Q)SAR. Naznake opasnih toksikoloških ili ekotoksikoloških svojstava kao i informacije o primjenama i ostale dostupne relevantne informacije moraju se usporediti s kriterijima iz Priloga III.

Činjenica da neka tvar nije na tom popisu ne mora značiti da nisu ispunjeni kriteriji iz Priloga III. Slično tomu, ako je neka tvar uvrštena u inventar, podnositelj registracije ipak može iskoristiti mogućnost dostavljanja informacija u smanjenom obujmu ako za to postoji opravdanje.

Napominjemo da popis nije alat za razvrstavanje, nego samo ukazuje na razloge za zabrinutost. Primjerice, činjenica da je tvar naznačena kao „potencijalni mutagen" ne znači da ECHA smatra kako je ta tvar razvrstana kao mutagen. Svi bi se dokazi trebali uzeti u obzir prije nego što se donese odluka o razvrstavanju.

Phenanthrene

EC / List no.: 201-581-5 CAS no.: 85-01-8
Information source
# Suspected bioaccumulative: KNN BCF model in VEGA (Q)SAR platform predicts a BCF of 3.312 log(L/kg) (EXPERIMENTAL value); Meylan BCF model in VEGA (Q)SAR platform predicts a BCF of 3.4 log(L/kg) (EXPERIMENTAL value); Bioaccumulation Canada database in the Toolbox reports at least one value above the B threshold of 2,000 L/Kg (3.3 log units) # Suspected carcinogen: The Toolbox profiler 'Carcinogenicity (genotox and nongenotox) alerts by ISS' gives an alert for carcinogenicity # Suspected hazardous to the aquatic environment: DEMETRA Daphnia Magna toxicity model in VEGA (Q)SAR platform predicts that the chemical has a 48h EC50 of 0.0972 mg/L (good reliability); EPA Daphnia Magna toxicity model in VEGA (Q)SAR platform predicts that the chemical has a 48h EC50 of 0.776 mg/L (EXPERIMENTAL value); Fathead Minnow toxicity model (EPA) in VEGA (Q)SAR platform predicts that the chemical has a 96h LC50 of 3.14 mg/L (moderate reliability); Fish toxicity classification (SarPy/IRFMN) model in VEGA (Q)SAR platform predicts that the chemical is 'Toxic-2 (between 1 and 10 mg/l) (good reliability)'; Fish Acute Toxicity model (KNN/Read-Across) in VEGA (Q)SAR platform predicts that the chemical has a 96h LC50 of 1.4 mg/L (EXPERIMENTAL value);The Danish QSAR database contains information indicating that the substance has a 96h LC50 to fish of 1.15 mg/L; The Danish QSAR database contains information indicating that the substance has a 48h EC50 to Daphnia of <1 mg/L # Suspected mutagen: The Toolbox profiler 'DNA alerts for AMES, MN and CA by OASIS v.1.3' gives an alert for mutagenicity; The Toolbox profiler 'in vitro mutagenicity (Ames test) alerts by ISS' gives an alert for mutagenicity; CAESAR Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Mutagen (EXPERIMENTAL value); ISS Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Mutagen (moderate reliability); KNN Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Mutagen (moderate reliability); SARPY Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Mutagen (EXPERIMENTAL value) # Suspected persistent in the environment: Ready biodegradability model (IRFMN) in VEGA (Q)SAR platform predicts that the chemical is Possible NON Readily Biodegradable (moderate reliability); Biodegradation NITE database in the Toolbox contains at least one experimental data from 28 days ready biodegradability test (OECD TG 301C or 301D) reporting a value lower than 60%;The Danish QSAR database contains information indicating that the substance is predicted as non readily biodegradable # Suspected skin sensitiser: CAESAR skin sensitisation model in VEGA (Q)SAR platform predicts that the chemical is Sensitizer (good reliability)

Download the full Annex III Inventory

You can download the full Annex III inventory as XLS format.

Download Annex III Inventory

 

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