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Diss Factsheets
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EC number: 291-010-6 | CAS number: 90295-19-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From January 28th to February 05th, 2016
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Remarks:
- Deviations from test guidelines occurred and do not permit to follow the guideline procedures.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- as revised in 1997
- Deviations:
- yes
- Remarks:
- deviations do not permit to follow the guideline procedures
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- deviations do not permit to follow the guideline procedures
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Water solubility:
- ca. 150 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 150 g/L
- Incubation duration:
- 3 d
- Temp.:
- 20 °C
- Remarks on result:
- other: it is not possible to determine absolute test substance water solubility by flask method; however, based on microscopy observetion the mixtures were homogeneous in all flasks.
- Details on results:
- Afier three days of shaking the mixtures had very viscous almost pasty consistency. Mixtures practically did not flow. Therefore it was not possible to shake or stir the mixtures. Undissolved surplus of the test substance was not found. Based on the microscopy observation the mixtures were homogeneous in all flasks. It was confirmed that all test substance was dissolved in solvent, therefore saturated solutions were not prepared. However, it was not possible to continue in further testing. Due to properties of the test substance mixtures it was not possible to fulfilled A.6 method and OECD Test Guideline No 105 conditions.
It is not possible to determine absolute test substance water solubility by flask method due to the high viscosity of the test substance mixture with water. Mixtures practically did not flow. lt was not possible to shake or stir the mixtures.Expected solubility in water should be higher than 150 g/l.
PRELIMINARY TEST
The determined solubility is greater than 0.01 g/l. Therefore the flask method was chosen to the main test. - Conclusions:
- Expected solubility in water should be higher than 150 g/l.
- Executive summary:
Water solubility test was performed for the test substance. Flask method was used. Three flasks were used for test. 30.00 g of the test substance was weighed into each one of three stoppered glass flasks. The volume of 200 ml of double distilled water was added into each of them. The glass vessels were tightly closed with glass stoppers and shaken in a shaking water bath at the temperature of 30° C within one, two and three days. After the shaking had been finished, the solutions were tempered down to 20 ± 0.1 °C for a period 24 hours. Afier three days of shaking the mixtures had very viscous almost pasty consistency. It was not possible to determine absolute test substance water solubility by flask method due to the high viscosity of the test substance mixture with water. Mixtures practically did not flow. lt was not possible to shake or stir the mixtures.
Expected solubility in water should be higher than 150 g/l.
Conclsuion
The water solubility of the test substance established by the flask method is higher than 150 g/l.
Reference
Description of key information
Expected solubility in water should be higher than 150 g/l.
Key value for chemical safety assessment
- Water solubility:
- 150 g/L
- at the temperature of:
- 20 °C
Additional information
Flask method - It was not possible to determine absolute test substance water solubility by flask method due to the high viscosity of the test substance mixture with water. Mixtures practically did not flow. It was not possible to shake or stir the mixtures.
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