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Diss Factsheets
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EC number: 701-197-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.166 mg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 1.05 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.017 mg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 100 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.764 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.076 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.055 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Derivation of PNECs
The PNECs for the different compartment can be calculated either by applying an assessment factor (PNECfreshwater, marine water, intermittent release and STP) or using the Equilibrium Partitioning Method (PNECsediment freshwater, sediment marine water and soil). The PNECoral and PNECair are considered as not relevant. The utilized procedures are described in detail in the ECHA REACH Guidance of May 2008, Chapter R.10 ("Guidance on information requirements and chemical safety assessment").
Environmental classification and labelling
Experimental investigations were performed in order to investigate the toxicity of 1,2,3-Propanetriol, glycidyl ethers towards aquatic microorganisms, green algae and daphnids. The toxicity towards Daphnia magna was conducted with an exposure time of 21 days (long-term test). The potential of short-term toxicity to daphnids, as well as short- and long-term toxicity towards fish were predicted with the scientifically accepted QSAR tool EPIWIN (software ECOSAR v1.00 and v0.99g by US-EPA). For chemical safety assessment (CSA), the experimental results are taken more into account; however, the QSAR predictions support the experimental results for the test substance.
The toxicity experiment with the algae species Pseudokirchneriella subcapitata (OECD Guideline 201; Liedtke, 2013) revealed an ErC50(72h) > 120 mg/L, thus indicating that there is no acute hazard potential towards this organisms. The long-term exposure to Daphnia magna revealed a No Observed Effect Concentration (NOEC) of 8.3 mg/L (OECD Guideline 211; Liedtke, 2013). As supporting information, the predicted Chronic Values (ChVs, reveal the geometric mean of the LOEC and NOEC) of the three trophic levels (fish, daphnids and algae) indicates that there is no toxicity concern (Chemservice S.A., 2015c).
In a Manometric Respirometry Test, conducted in accordance with OECD Guideline 301F the test substance was found to be not readily biodegradable so that the substance is considered as persistent in the environment (please refer to PBT assessment). However, 24 % degradation were attained within 55 days exposure period. Furthermore, bioaccumulation is not expected, based on the predicted Bioconcentration Factor (BCF) of 3.16 L/kg w.w. by BCFBAFv3.01 (Chemservice S.A., 2013).
Concerning all available data and in reference to Regulation (EC) No. 1272/2008, 1,2,3-Propanetriol, glycidyl has not to be classified and labelled with respect to environmental hazards.Conclusion on classification
In accordance to Regulation (EC) No. 1272/2008 (Classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No. 1907/2006), 1,2,3-Propanetriol, glycidyl has not to be classified and labelled with respect to environmental hazards.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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