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EC number: 200-352-7 | CAS number: 57-87-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Solubility in organic solvents / fat solubility
Administrative data
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- not specified
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Solubility in organic solvents
- Author:
- Lide D.R.
- Year:
- 2 008
- Bibliographic source:
- Lide D.R., CRC Handbook of Chemistry and Physics 88th Edition 2007-2008, CRC Press, Taylor & Francis, p. 3-320 (2008); Lide D.R., CRC Handbook of Chemistry and Physics 88th Edition 2007-2008, CRC Press, Taylor & Francis, p. 3-320 (2008)
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- method not known
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Ergosterol
- EC Number:
- 200-352-7
- EC Name:
- Ergosterol
- Cas Number:
- 57-87-4
- Molecular formula:
- C28H44O
- IUPAC Name:
- ergosta-5,7,22-trien-3-ol
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Solubility in organic solvents / fat solubilityopen allclose all
- Key result
- Medium:
- other: chloroform
- Solubility:
- 20 g/kg solvent
- Temp.:
- 18 °C
- Key result
- Medium:
- diethyl ether
- Solubility:
- 20 g/kg solvent
- Temp.:
- 20 °C
- Key result
- Medium:
- acetone
- Solubility:
- 5 g/kg solvent
- Temp.:
- 22 °C
- Key result
- Medium:
- benzene
- Solubility:
- 10.638 g/kg solvent
- Temp.:
- 16 °C
Any other information on results incl. tables
Value:1 g / 50 g chloroform (18°C)
Reference:Tanret M.C., Sur l’ergostérine et la fongistérine, Annales de Chimie, Serie 8,15,
p. 313-330 (1908);
Reference:Tanret, Bulletin de la Société Chimique de France, Serie 4,31, p. 444-446 (1922);
***
Value:1 g / 31 ml chloroform
Reference:The Merck Index – An Encyclopedia of Chemicals, Drugs and Biologicals, O’Neil
M.J. (editor), Merck & Co., p. 626 (2006);
***
Value:1 g / 50 g diethyl ether (20°C)
1 g / 28 g diethyl ether (boiling)
Reference:Tanret M.C., Sur l’ergostérine et la fongistérine, Annales de Chimie, Serie 8,15,
p. 313-330 (1908);
Reference:Tanret, Bulletin de la Société Chimique de France, Serie 4,31, p. 444-446 (1922);
***
Value:14.286 g/l diethyl ether (boiling)
Reference:Honeywell E.M., Bills Ch.E., Cerevisterol, a sterol accompanying ergosterol in
yeast, Journal of Biological Chemistry,99(1), p. 71-78 (1932);
***
Value:1 g / 200 g acetone (22°C)
1 g / 32 g acetone (boiling)
Reference:Tanret M.C., Sur l’ergostérine et la fongistérine, Annales de Chimie, Serie 8,15,
p. 313-330 (1908);
Reference:Tanret, Bulletin de la Société Chimique de France, Serie 4,31, p. 444-446 (1922);
***
Value:37.037 g/l acetone (boiling)
Reference:Honeywell E.M., Bills Ch.E., Cerevisterol, a sterol accompanying ergosterol in
yeast, Journal of Biological Chemistry,99(1), p. 71-78 (1932);
***
Value:153.846 g/l ethyl acetate (boiling)
Reference:Honeywell E.M., Bills Ch.E., Cerevisterol, a sterol accompanying ergosterol in
yeast, Journal of Biological Chemistry,99(1), p. 71-78 (1932);
***
Value:28.571 g/l methyl acetate (boiling)
Reference:Honeywell E.M., Bills Ch.E., Cerevisterol, a sterol accompanying ergosterol in
yeast, Journal of Biological Chemistry,99(1), p. 71-78 (1932);
***
Value:100 g/l 2-propanol (boiling)
Reference:Honeywell E.M., Bills Ch.E., Cerevisterol, a sterol accompanying ergosterol in
yeast, Journal of Biological Chemistry,99(1), p. 71-78 (1932);
***
Value:1 g / 94 g benzene (16°C)
Reference:Tanret M.C., Sur l’ergostérine et la fongistérine, Annales de Chimie, Serie 8,15,
p. 313-330 (1908);
Reference:Tanret, Bulletin de la Société Chimique de France, Serie 4,31, p. 444-446 (1922);
***
Value:217.391 g/l benzene (boiling)
Reference:Honeywell E.M., Bills Ch.E., Cerevisterol, a sterol accompanying ergosterol in
yeast, Journal of Biological Chemistry,99(1), p. 71-78 (1932);
***
Value:41.667 g/l hexane (boiling)
Reference:Honeywell E.M., Bills Ch.E., Cerevisterol, a sterol accompanying ergosterol in
yeast, Journal of Biological Chemistry,99(1), p. 71-78 (1932);
***
Value:3.571 g/l methanol (boiling)
Reference:Honeywell E.M., Bills Ch.E., Cerevisterol, a sterol accompanying ergosterol in
yeast, Journal of Biological Chemistry,99(1), p. 71-78 (1932);
***
Value:20 g/l ethanol (boiling)
Reference:Honeywell E.M., Bills Ch.E., Cerevisterol, a sterol accompanying ergosterol in
yeast, Journal of Biological Chemistry,99(1), p. 71-78 (1932);
***
Value:1 g / 526 g ethanol/water
1 g / 36 g ethanol/water (boiling)
Reference:Tanret M.C., Sur l’ergostérine et la fongistérine, Annales de Chimie, Serie 8,15,
p. 313-330 (1908);
Reference:Tanret, Bulletin de la Société Chimique de France, Serie 4,31, p. 444-446 (1922);
***
Value:slightly soluble in ethanol, ethyl ether, petroleum ether; soluble in benzene,
chloroform
Reference:Lide D.R., CRC Handbook of Chemistry and Physics 88thEdition 2007-2008, CRC
Press, Taylor & Francis, p. 3-320 (2008);
Applicant's summary and conclusion
- Conclusions:
- Slightly soluble in ethanol, ethyl ether, petroleum ether; soluble in benzene,chloroform.
- Executive summary:
1 g / 50 g chloroform (18°C)
1 g / 31 ml chloroform
1 g / 50 g diethyl ether (20°C)
1 g / 28 g diethyl ether (boiling)
14.286 g/l diethyl ether (boiling)
1 g / 200 g acetone (22°C)
1 g / 32 g acetone (boiling)
37.037 g/l acetone (boiling)
153.846 g/l ethyl acetate (boiling)
28.571 g/l methyl acetate (boiling)
100 g/l 2-propanol (boiling)
1 g / 94 g benzene (16°C)
217.391 g/l benzene (boiling)
41.667 g/l hexane (boiling)
3.571 g/l methanol (boiling)
20 g/l ethanol (boiling)
1 g / 526 g ethanol/water
1 g / 36 g ethanol/water (boiling)
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