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Diss Factsheets
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EC number: 205-619-1 | CAS number: 144-19-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
readily biodegradable |
Additional information
Two ready biodegradation studies have been performed on 2,2,4-trimethylpentanediol (TMPD). The key study was conducted using the DOC Die-Away Test (OECD Guideline 301A). In that study a lag phase of approximately 3 - 4 days occurred before biodegradation reached 10% in both test vessels. The test substance reached 91% and 98% degradation within the subsequent 10-day window. At test end, the test substance showed 99% and 100% degradation (as measured by loss of DOC). In the second study based upon CO2 evolution an average of 87.8% biodegradation was observed within 28 days. Based upon the results of these studies the substance meets the criteria to be considered readily biodegradable.
In addition to the ready biodegradation studies, a wastewater treatment plant simulation study was conducted using a Semi-Continuous Activated Sludge (SCAS) Removability Test. This test is designed to determine the removability of the test substances in the SCAS test system, as measured by soluble organic carbon (SOC). In this study the sludge organisms were incrementally acclimated to TMPD over 7 days followed by a 7 day test period. During the 7 day test period SOC was measured in samples removed from the control and test substance replicates. The volume of sample removed was replaced with a comparable volume of fresh influent containing the test substance and synthetic sewage and the process was repeated each day. The results of these daily analyses over the 7 day test period was a daily mean removal of 101% with a 95% confidence interval of ± 1.6%.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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