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EC number: 212-603-8 | CAS number: 831-52-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: estimated by calculation
- Justification for type of information:
- estimated by calculation
- Qualifier:
- according to guideline
- Guideline:
- other: Modeling database
- Principles of method if other than guideline:
- Estimation of 96 hr EC50 value of test chemical by modelling Database - ECOSAR v.1.11. The ECOSAR Class Program is a computerized version of the ECOSAR analysis procedures as currently practiced by the Office of Pollution Prevention and Toxics (OPPT). It has been developed within the regulatory constraints of the Toxic Substances Control Act (TSCA). It is a pragmatic approach to SAR. The structure-activity relationships (SARs) presented in this program are used to predict the aquatic toxicity of chemicals based on their similarity of structure to chemicals for which the aquatic toxicity has been previously measured. Most SAR calculations in the ECOSAR Class Program are based upon the octanol/water partition coefficient (Kow). Various surfactant SAR calculations are based upon the average length of carbon chains or the number of ethoxylate units.
- GLP compliance:
- no
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Daphnia magna
- Test type:
- not specified
- Water media type:
- not specified
- Total exposure duration:
- 48 h
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 1 637.454 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: not specified
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The Lethal concentration (LC50) value of test material in aquatic invertebrate (Daphnia Magna) in a 48 hr study based on mortality effect was estimated to be 1637.454 mg/L.
- Executive summary:
The Lethal concentration (LC50) value of test material in aquatic invertebrate (Daphnia Magna) in a 48 hr study based on mortality effect was estimated to be 1637.454 mg/L. Thus considering the value from CLP Criteria for aquatic classification of the substance , it is concluded that test material does not exhibit short term toxicity aquatic invertebrate (Daphnia Magna) in the present test condition.
Reference
Description of key information
Short term toxicity to aquatic invertebrates:
The Lethal concentration (LC50) value of test material in aquatic invertebrate (Daphnia Magna) in a 48 hr study based on mortality effect was estimated to be 1637.454 mg/L. Thus considering the value from CLP Criteria for aquatic classification of the substance , it is concluded that test material does not exhibit short term toxicity aquatic invertebrate (Daphnia Magna) in the present test condition.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1 637.454 mg/L
Additional information
Short term toxicity to aquatic invertebrates:
The toxicity of test material was evaluated for aquatic invertebrate based on the predicted data and data for structurally similar read across substance from peer reviewed journal.
The Lethal concentration (LC50) value of test material in aquatic invertebrate (Daphnia Magna) in a 48 hr study based on mortality effect was estimated to be 1637.454 mg/L. Thus considering the value from CLP Criteria for aquatic classification of the substance , it is concluded that test material does not exhibit short term toxicity aquatic invertebrate (Daphnia Magna) in the present test condition.
The above prediction was supported by data from peer reviewed journal for structurally similar read across substance ,Short term toxicity of test material was evaluated on aquatic invertebrate , for 24 h .The dilution water used had a specific composition: acid capacity Ks4.3 of 0.8mmoll -I total hardness of 2.4 mmol/l , a calcium to magnesium ratio of 4:1, a sodium to potassium ratio of 10:1 and thus a resulting initial pH value of 8.0 + 0.2. 6-24 h old daphnids were used , test was carried out in 50 ml beakers with ground-glass stoppers each with 20 ml useful capacity. The effect concentration noted after 24 h was observed to be 123 mg/l. Based on the above effect concentration it can be considered that test material is not toxic to daphnia magna and hence, can not be classified as per CLP criteria.
Another study , for structurally similar read across substance stated that toxicity of test material was evlauted on American Oysters . Clutchless American oysters (x = 48.4 ± 6.2 mm shell height) were purchased from the Wilde Oyster Hatchery, Shady Side, Maryland.test organisms were obtained at approximately 10 C and acclimated in the laboratory for a minimum of two weeks at 10 (+ 1) C under a 12 hlight:12 h dark photoperiod prior to and during testing. Oysters were fed natural plankton in the estuarine water system supplemented with 1.5 percent corn starch-yeast solution when necessary.One replicate of 20 organisms was used at each test concentration , the concentrations used were 0, 25, 50, 100, 150, and 200 mg/l. The effect of test material was on organism American Oysters for 144 h , was observed to be 254.9 mg/l.
Based on the above effect concentration it can be concluded that test material is not toxic to aquatic invertebrates.
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