Registration Dossier
Registration Dossier
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EC number: 413-110-2 | CAS number: 135861-56-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Marine water fish
Marine water fish
- Effect concentration:
- 0.1 mg/L
Additional information
An acute toxicity to fish study was conducted for T-1540N (Safepharm Laboratories, 2001). The study was conducted according to EEC test method C.1. The 96 -hour LC50 to Oncorhynchus mykiss (previously called Salmo gairdineri) was found to be greater than 0.1mg/L.
The test concentration of 0.10 mg/l was the highest attainable test concentration due to the limited solubility of the test material in water and auxiliary solvent, and having due regard for the amount of auxiliary solvent permitted in the test under the OECD Guielines.
Analysis of the test solutions at 0, 24 and 96 hours showed the measured test concentrations to be in excess of the required 80% of nominal, and so the results are based on nominal test concentrations only. 96 hour NOEC>=0.1mg/l.
An acute toxicity to fish study was conducted for T-1540N (SPFC, 2001). The study was conducted according toOECD guideline 203. The 96 -hour LC50 to Zebra fish was found to be greater than 0.05mg/L.
- No auxiliary substance could help to solubilize the test substance.
- Considering the low water-solubility of the test substance and in order to prevent impact of solid particles, the test substance was prepared as follows : a 1000 mg/l suspension was stirred for 2 hours ; the substance in excess was then filtered. The saturated solution obtained was used as such and diluted (100 % to 25 %). No mortality nor any abnormal behaviour were noted at any of these concentrations.
- Analysis confirmed highest concentration
96 hour NOEC>=0.05mg/l.
It will be concluded that test material T-1540N did not meet classification criteria for toxicity to fish.
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