Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
A study with P. subcapitata is available (reliability 1) performed according to OECD and GLP guidelines.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.33 mg/L
- EC10 or NOEC for freshwater algae:
- 0.09 mg/L
Additional information
In a 72-hour algal growth inhibition test, exponentially growing algae were exposed to dilutions of a paper filtrate of a stock solution prepared at 100 mg/L. As measured concentrations in these solutions all exceeded the solubility level of the test substance, an additional solution was prepared as a 0.22 µm filtrate of a stock solution prepared at 100 mg/L.
Algal growth was inhibited in a dose-responsive relation in the solutions prepared as dilutions of the paper filtrate, but was not affected in the fine filtrate. The 72-hour EC50 values of the test substance are 0.33 mg/L (growth rate), 0.26 mg/L (biomass) and 0.24 mg/L (yield). The 72-hour NOEC for growth rate, biomass and yield is 0.09 mg/L. These values exceed the solubility limit of the test substance in test medium.
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