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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

Key value for chemical safety assessment

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Focusing on environmental effects assessment, long term data obtained for chronic ecotoxicity of the formulation (fenoxaprop-P-ethyl + AE F122006) were used as read across for fish. The tested concentrations of formulated test substance were 0.09, 0.15, 0.25, 0.42, and 0.70 mg/L. The mean measured concentrations of the safener (AE F122006) were 78 to 87% of nominal concentrations based on 7.30% w/w of this formulation. The mean measured concentrations of the active ingredient (AE F046360) were 90 to 115% of nominal concentrations based on 6.95 % w/w of this formulation.

As the test compound consists of one active ingredient, a safener, and formulation additives, degradation or adsorption behavior of the active ingredient is not necessarily indicative of the behavior of the other ingredients. Since the toxicity cannot be unequivocally attributed to only the measured active ingredient or safener, no adjustment of results for measured concentrations was made. Therefore, all toxicity values were calculated based on the nominal concentrations of the fenoxaprop-P-ethyl + AE F122006 emulsifiable concentrate added to the test water.

Based on growth of fish during this study, the NOEC (No Observed Effect Concentration) is the nominal concentration of 0.42 mg/L and the LOEC (Lowest Observed Effect Concentration) is the nominal concentration of 0.70 mg/L. The 28 day EC50 was 0.65 mg/L.

Using these values in the risk assessment represents a worst case situation for the risk assessment of the safener and is sufficiently adequate for a conservative risk assessment. Therefore as a reasonable worst-case approach, the lowest long term NOEC is 0.42 mg/L.