Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP-Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1995
Report Date:
1995

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Remarks:
Senatsverwaltung für Gesundheit, Berlin
Type of method:
effusion method: vapour pressure balance

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Ethyl-5,5-diphenyl-2-isoxazoline-3-carboxylate
- Internal no.: Hoe 122006
- Analytical purity: 99.6% (Certificate of analysis C/061/95)
- Physical state: fine white powder
- Storage conditions: released until October 12th, 1995
- Lot/batch No.: R001413

Results and discussion

Vapour pressure
Temp.:
20 °C
Vapour pressure:
0 Pa
Remarks on result:
other: extrapolated value

Any other information on results incl. tables

t [°C]

P(Pa)

95 % CI

20*

2.2 ·10-6

9.3 ·10-7- 5.1 ·10-6

25*

5.5 ·10-6

2.5 ·10-6- 1.2 ·10-5

30*

1.3 ·10-5

6.3 ·10-6- 2.6 ·10-5

66

2.9 ·10-3

2.1 · 10- 3- 4.5 ·10-3

75

1.08 ·10-2

7 ·10-3 - 1.5 ·10-2

94*

0.105

6.8 ·10-2- 0.16

104*

0.32

0.196 - 0.53

 

*) - extrapolated values of vapour pressure

t - temperature (°C)

p - vapour pressure (Pa)

95% CI - 95 % confidence interval

 

The good agreement of the experiments at different temperatures provides evidence that the samples being measured are sufficiently pure and are not decomposing in the respective range of temperatures.

Applicant's summary and conclusion