Registration Dossier
Registration Dossier
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EC number: 690-742-7 | CAS number: 1266664-66-7
Endpoint summary
Administrative data
Description of key information
The LD50 was greater than 300 mg/kg bw, but less than 2000 mg/kg bw in rats. Accordingly, the test item was considered to be in Acute Toxic Category 4.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 300 mg/kg bw
Additional information
At a single oral dose of 2000 mg/kg bw, all three animals died. Ante-mortem clinical signs included convulsions, negative righting reflex, brown staining of the mouth/nose area and rigid muscle tone. All six animals survived a single 300 mg/kg bw dose. At the 300 mg/kg bw dose, the only clinical signs were brown staining of the nose/mouth area in one animal.
Justification for classification or non-classification
The substance meets classification criteria under EU Directive 67/548/EEC for acute oral toxicity.
The substance meets classification criteria under Regulation (EC) No 1272/2008 for Acute Toxicity - Oral, Category 4.
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