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Diss Factsheets

Physical & Chemical properties

Flash point

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Administrative data

Endpoint:
flash point of flammable liquids
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
20 February 2017 to 02 March 2018
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: The test item solidified

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.9 (Flash-Point)
Deviations:
no
Qualifier:
according to guideline
Guideline:
ISO 2719 (Determination of flash point - Pensky-Martens closed cup method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
ASTM D93 (Standard test methods for flash point by pensky-martens closed cup tester)
Deviations:
no
Qualifier:
according to guideline
Guideline:
ISO 3679 (Determination of flash point - Rapid equilibrium closed cup method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: UN no. ST/SG/AC.10/11/Rev.6 (Non-Viscous Flammable Liquids)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: ASTM D7094 (Standard Test Method for Flash Point by Modified Continuously Closed Cup (MCCCFP) Tester)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
equilibrium method closed cup
Flash point apparatus:
other: Eraflash flash-point tester (Eralytics, Vienna, Austria)

Test material

Constituent 1
Chemical structure
Reference substance name:
(2R)-6-fluoro-2-[(2S)-oxiran-2-yl]-3,4-dihydro-2H-1-benzopyran
EC Number:
603-315-7
Cas Number:
129050-26-6
Molecular formula:
C11H11FO2
IUPAC Name:
(2R)-6-fluoro-2-[(2S)-oxiran-2-yl]-3,4-dihydro-2H-1-benzopyran
Test material form:
other: wax
Details on test material:
Physical state: wax form
Appearance: clear, viscous, wax
Specific details on test material used for the study:
- Batch n°: I16HB3199
- Analytical purity: 98.9%
- Expiration date: 2017-09-13 (retest date)
- Storage condition: at room temperature

Results and discussion

Flash point
Key result
Flash point:
<= 23 °C
Atm. press.:
101.325 kPa
Remarks on result:
other: atmospheric pressure not reported.

Any other information on results incl. tables

Preliminary test

The estimated flash-point of the test item was≤40°C since a flash was observed at the start of the second preliminary test. A preliminary test with a lower temperature was not possible because of the melting temperature.

 

Equilibrium method

A flash was observed at the start temperature of 23°C. Therefore, the flash point was≤23°C.

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Remarks:
The test item solidified at room temperature; the melting point was determined to be 43.8°C and the determined flash-point was below the melting point; for this reason the study is considered not reliable
Conclusions:
The closed cup method was applied for the determination of the flash-point of JNJ-17337359-AAA (T001590).
The flash-point of the test item obtained with the equilibrium method was ≤23°C.