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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Remarks:
VEGA QSAR Daphnia Magna LC50 48h DEMETRA 1.0.4.
Adequacy of study:
key study
Study period:
2018-2019
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
VEGA QSAR Daphnia Magna LC50 48h DEMETRA 1.0.4.

Data source

Reference
Reference Type:
other: QSAR Data
Title:
Daphnia Acute Toxicity Key Salicylates
Author:
VEGA
Year:
2018
Bibliographic source:
VEGA QSAR Daphnia Magna LC50 48h DEMETRA 1.0.4
Report Date:
2019

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
VEGA QSAR Daphnia Magna LC50 48h DEMETRA 1.0.4.

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Test organisms

Test organisms (species):
Daphnia magna

Results and discussion

Effect concentrationsopen allclose all
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 1.81 mg/L
Remarks on result:
not measured/tested
Remarks:
no effect up to the limit of the substance water solubility was observed in Octyl Salicylate (QSAR elaboration)
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 1.1 mg/L
Remarks on result:
not measured/tested
Remarks:
no effect up to the limit of the substance water solubility was observed in Nonyl Salicylate (QSAR elaboration)
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 0.688 mg/L
Remarks on result:
not measured/tested
Remarks:
no effect up to the limit of the substance water solubility was observed in Decyl Salicylate (QSAR elaboration)
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 0.82 mg/L
Remarks on result:
not measured/tested
Remarks:
no effect up to the limit of the substance water solubility was observed in Isodecyl Salicylate (QSAR elaboration)
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 0.355 mg/L
Remarks on result:
not measured/tested
Remarks:
no effect up to the limit of the substance water solubility was observed in Undecyl Salicylate (QSAR elaboration)
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 0.274 mg/L
Remarks on result:
not measured/tested
Remarks:
no effect up to the limit of the substance water solubility was observed in Dodecyl Salicylate (QSAR elaboration)
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 0.178 mg/L
Remarks on result:
not measured/tested
Remarks:
no effect up to the limit of the substance water solubility was observed in Tridecyl Salicylate (QSAR elaboration)
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 0.16 mg/L
Remarks on result:
not measured/tested
Remarks:
no effect up to the limit of the substance water solubility was observed in Isotridecyl Salicylate (QSAR elaboration)
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 0.119 mg/L
Remarks on result:
not measured/tested
Remarks:
no effect up to the limit of the substance water solubility was observed in Tetradecyl Salicylate (QSAR elaboration)
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 0.05 mg/L
Remarks on result:
not measured/tested
Remarks:
no effect up to the limit of the substance water solubility was observed in Hexadecyl Salicylate (QSAR elaboration)

Applicant's summary and conclusion

Conclusions:
no effect up to the limit of the substance water solubility was observed.