Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
density
Remarks:
density
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Scientifically accurate study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
EU Method A.3 (Relative Density)
Deviations:
not specified
GLP compliance:
no
Type of method:
pycnometer method

Test material

Constituent 1
Chemical structure
Reference substance name:
α-methyl-1H-imidazole-1-ethanol
EC Number:
253-668-2
EC Name:
α-methyl-1H-imidazole-1-ethanol
Cas Number:
37788-55-9
Molecular formula:
C6H10N2O
IUPAC Name:
1-(1H-imidazol-1-yl)propan-2-ol
impurity 1
Chemical structure
Reference substance name:
2-(1H-imidazol-1-yl)propan-1-ol
Molecular formula:
C6H10N2O
IUPAC Name:
2-(1H-imidazol-1-yl)propan-1-ol
impurity 2
Chemical structure
Reference substance name:
1-{[1-(1H-imidazol-1-yl)propan-2-yl]oxy}propan-2-ol
Molecular formula:
C9H16N2O2
IUPAC Name:
1-{[1-(1H-imidazol-1-yl)propan-2-yl]oxy}propan-2-ol
impurity 3
Chemical structure
Reference substance name:
2-{[1-(1H-imidazol-1-yl)propan-2-yl]oxy}propan-1-ol
Molecular formula:
C9H16N2O2
IUPAC Name:
2-{[1-(1H-imidazol-1-yl)propan-2-yl]oxy}propan-1-ol
Test material form:
liquid

Results and discussion

Density
Key result
Type:
density
Density:
ca. 1.11 g/cm³
Temp.:
20 °C

Any other information on results incl. tables

Two 25 ml pycnometers were used, thermostat M3 Lauda with accurarcy 0,1 °C, Sartorius AX 124 analytical balance with accurarcy 0,0001 g where used.

measurements at 20 °C

mass of 1st picnometer: 16.3128 g

mass of water filled 1st picnomter: 41.2288 g

mass of 1st pycnometer filled with the sample: 44.0347 g

density of water at 20 °C: 0.9982 g/cm3

density of the sample: 1.1106 g/cm3

mass of 2nd pycnometer: 21.2146 g

mass of water filled 2nd pycnometer: 46.1333 g

mass of 2nd pycnometer filled with the sample: 48.9305

density of water at 20 °C: 0.9982 g/cm

density of the sample: 1.1102 g/cm3

mean value for the density: 1.1104 g/cm3

Applicant's summary and conclusion

Executive summary:

The density of N-(2-hydroxypropyl)imidazole at 20 °C is 1.1104 g/cm3.

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