Registration Dossier
Registration Dossier
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EC number: 814-059-2 | CAS number: 68680-98-8
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1973
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 973
- Report date:
- 1973
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Not specified.
- GLP compliance:
- no
- Remarks:
- Test carried out prior to GLP
- Test type:
- fixed dose procedure
- Limit test:
- yes
Test material
- Reference substance name:
- 3,7-dimethyloctan-1-ol
- EC Number:
- 203-374-5
- EC Name:
- 3,7-dimethyloctan-1-ol
- Cas Number:
- 106-21-8
- Molecular formula:
- C10H22O
- IUPAC Name:
- 3,7-dimethyloctan-1-ol
Constituent 1
Test animals
- Species:
- other: Not specified
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- 14 days
- No. of animals per sex per dose:
- 6
- Control animals:
- no
- Details on study design:
- 6 animals dosed
Results and discussion
- Preliminary study:
- none
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- < 5 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- After 14 days:
- 4 animals found dead at the dose level tested.
Moderate erythema, morbidity (lethargy, malaise), prostration, coma and death. - Clinical signs:
- other: Not specified
- Gross pathology:
- Dried cracked skin noted, persisting for 14 days.
- Other findings:
- See attachment.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The test substance tested has an acute dermal LD50 of < 5.0 g/kg.
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