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EC number: 222-048-3
CAS number: 3327-22-8
Concentration: 65%, dose 7028 µg/cm2
Flux constant [µg cm-2 h-1]: 18.5 ± 13.0
Kp-value [cm h-1]: 0.026 ± 0.018
Lag time [h]: 0.1 ± 0.2
Relative skin absorption after 48 h: 13.9%
Concentration: 20%, dose 1966 µg/cm2
Flux constant [µg cm-2 h-1]: 21.0 ± 13.6
Kp-value [cm h-1]: 0.107 ± 0.069
Lag time [h]: 0.2 ± 0.4
Relative skin absorption after 48 h: 40.9%
Concentration: 1%, dose 94.6 µg/cm2
Flux constant [µg cm-2 h-1]: 0.61 ± 0.7
Kp-value [cm h-1]: 0.065 ± 0.074
Lag time [h]: 1.8 ± 0.4
Relative skin absorption after 48 h: 22.6%
Concentration: 0.1%, dose 9.73 µg/cm2
Flux constant [µg cm-2 h-1]: 0.15 ± 0.12
Kp-value [cm h-1]: 0.151 ± 0.128
Lag time [h]: 1.3 ± 0.6
Relative skin absorption after 48 h: 43.6%
The amount of radioactivity on the skin after stripping was
5.3 to 17.6-fold lower than the amount of radioactivity in
the receptor fluid. The mean recovery of radioactivity was between 91.2
and 102.2 %.
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