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Administrative data

Endpoint:
relative self-ignition temperature (solids)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-04-12 - 2017-04-20
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
other: UN Recommendations on the TRANSPORT OF DANGEROUS GOODS: Manual of Tests and Criteria, Rev. 6 (2015) and UN-Model Regulations, Rev. 19 (2015)
Qualifier:
according to guideline
Guideline:
other: VDI 2263 Sheet 1 Grewer Oven (1990)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(3,5-Dihydroxyphenyl)-1-oxo-2-(N-1-(4-methoxyphenyl)isopropylamino)ethane Hydrobromide
EC Number:
928-779-0
Molecular formula:
C18-H21-N-O4 x HBr
IUPAC Name:
1-(3,5-Dihydroxyphenyl)-1-oxo-2-(N-1-(4-methoxyphenyl)isopropylamino)ethane Hydrobromide
Test material form:
solid: particulate/powder

Results and discussion

Relative self-ignition temperature (solids)
Key result
Remarks on result:
no self ignition observed under the test conditions
Remarks:
The pure test item indicated a small self-heating at atmospheric pressure at a temperature of approx. 180 °C and turned into an endothermic process at 200 °C. No self-ignition was observed.

Any other information on results incl. tables

In the investigation of self-ignition in the Grewer Oven for the pure test item a small exothermic effect starts at approx. 180 °C and turns into an endothermic process at 200 °C, which can be assigned to the melting of the test item. After this the temperature of the test item was permanent over the reference temperature (5 – 10 K) until the maximum temperature of 425 °C (415 °C reference). This effect is explained to the changed physical condition of the test item. After the measurement the test item in the basket was changed to bloated black flakes.

For the test item in mixture with Kieselguhr an exothermic effect was observed at approximately 180 °C and 230 °C, which led to a maximum temperature of 630 °C.Table 1summarizes the results of the Grewer Oven experiment

Table1: Results of the screening test for self-ignition in the Gewer-Oven

Experiment

Onset self-
ignition / °C

Maximum temperature / °C

Remarks

Pure test item

---

425

Figure4,Figure5

Test item in mixture
with Kieselguhr (1:1)

180 / 230

630

Applicant's summary and conclusion

Conclusions:
The pure test item indicated a small self-heating at atmospheric pressure at a temperature of approx. 180 °C and turned into an endothermic process at 200 °C. No self-ignition was observed.