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EC number: 230-408-6
CAS number: 7098-80-8
In the acute immobilization test with Daphnia magna (STRAUS), the
effects of the test item Isoproylidenglycerolmethacrylate (IPGMA) were
determined according to OECD 202 (2004), which is equivalent to the
Council Regulation (EC) No.440/2008 Method C.2 (2008). The study was
conducted under semi-static conditions with renewal of the test
solutions in 24 hour intervals over a period of 48 hours with a limit
concentration of 120 mg/L of the test item
Isopropylidenglycerolmethacrylate (IPGMA). The tested concentration
level was visually clear throughout the exposure period. Twenty daphnids
(divided into 4 replicates with 5 daphnids each) were exposed to the
test item concentration and the control. Based on the nominal test item
concentration of the test item Isopropylidenglycerolmethacrylate
(IPGMA), the 48 hour-EC50 for Daphnia magna was > 120 mg/L and 48
hour-NOEC was >= 120 mg/L. The geometric mean measured concentration was
Aquatic algae and cyanobacteria:
The toxicity of Isopropylidenglycerolmethacrylate (IPGMA) to the
unicellular freshwater green alga Pseudokirchneriella subcapitata was
determined according to the principles of OECD 201 and Council
Regulation (EC) No. 761/2009 Method C.3. The study was conducted under
static conditions with an initial cell density of 6305 cells/ml. A stock
solution of 500 mg/L was freshly prepared with demineralized water and
stirred for 15 minutes (1100 rpm, room temperature). Seven
concentrations were tested in a geometrical series with a dilution
factor of 3.2: 0.466; 1.49; 4.77; 15.3; 48.8; 156.3; 500 mg/L,
corresponding to the geometric mean measured test item concentrations:
0.402 ;1.43; 4.90; 15.4; 53.3; 178; 558 mg/L. The environmental
conditions were within the acceptable limits. The concentrations of the
test item in all test concentrations and the control were analytically
verified by GC-MS at the start and the end of exposure. Based on the
geometric mean measured test item concentrations, the NOEC values (0-72
hours) for inhibition of growth rate and inhibition of yield were 15.4
mg/L and 1.43 mg/L. The EC50-values with 95% confidence intervals for
inhibition of growth rate (ErC50) and yield (EyC50) after 72 hours were
402 (344 - 455) mg/L and 125 (104 - 148) mg/L, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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