(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

21st August to 24 August 2006

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2006

Report date:

2006

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Test material

Test material information

Constituent 1

Details on test material:

Sponsor's identification: Experimental 20105-68

Results and discussion

Boiling point

Boiling pt.:

> 673 K

Atm. press.:

101.43 kPa

Decomposition:

yes

Any other information on results incl. tables

No value for the boiling temperature could be determined experimentally. However, using an adaptation of the Stein and Brown method, MPBPWIN version 1.41, © 2000 U.S. Environmental Protection Agency, the boiling temperature was calculated to be 816 K.

 

Small undulations were present from approximately 330°C (603 K). These undulations are possibly due to some decomposition and/or boiling of the test material. Upon opening the crucibles, a brown stain-like residue was evident, which is indicative of decomposition/ volatilisation. It was not possible to perform a visual assessment on the test material as the methods used are restricted to 360°C. The thermal events observed in the thermograrns occur after this temperature; therefore no further useful information would be obtained.

Applicant's summary and conclusion

Conclusions:

The boiling temperature of the test material has been determined to be >673 ± 0.5 K at 101.43 kPa.
A calculated value of boiling temperature gave a result of 816 K.

Executive summary:

In a general physico-chemical properties study (0656/0338), the test material was determined to have a boiling temperature of greater than 673 ± 0.5 K based on the DSC method, Method A2 of Commission Directive 92/69/EEC. A calculated value of boiling temperature gave a result of 816 K.