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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

EC50 = 902 mg/l

EC10 = 76.8 mg/l; EC20 = 179 mg/l; NOEC = 31.6 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
902 mg/L
EC10 or NOEC for microorganisms:
31.6 mg/L

Additional information

The toxicity to microorganisms of the substance was evaluated according to the OECD Guideline 209.

The total respiration rate of an activated sludge (inhibition of oxygen uptake by both micro-organisms oxidising organic carbon and by micro-organisms oxidising ammonium) fed with a standard amount of synthetic sewage feed was measured after a 3 hours exposure.

A non-GLP range finding test with the nominal concentrations of 10, 316 and 1000 mg/l was performed. based on the results obtained the definitive test was performed using the following concentrations: 1000, 316, 100, 31.6 and 10.0 mg/L.

After 3 hours of exposure the following effects on the activated sludge were observed:

EC50 = 902 mg/l

EC10 = 76.8 mg/l; EC20 = 179 mg/l; NOEC = 31.6 mg/L.