Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 211-185-4
CAS number: 632-79-1
1Temperature was continuously monitored in a container of water located adjacent to the study with an Amegaview Scientific centralized monitoring system.
Mean Measured Test Concentration (mg/L)
1Day 0 samples were collected from the individual batches of test solutions prepared for each treatment and control group at test initiation.
2Day 3 samples were from pooled samples of test solution collected from the three replicates per treatment and six replicates in the control group at test termination.
of R. subcapitata Growth After 72 Hours of Exposure to
72 Hours of Exposure1
Mean Cell Density (cell/mL)3*
Mean Growth Rate (hours-1)*
Mean Yield (cells/mL)3*
1Calculations were performed using SAS Version 9.4. Manual calculations may differ slightly.
2Inhibition was calculated relative to the mean negative control response.
3Yield was calculated as the final cell density minus the nominal initial cell density (10,000 cells/mL).
*None of the treatment group means were significantly different from the negative control mean (Dunnett’s test, P>0.05)
The objective of the study
was to determine the toxicity of Tetrabromophthalic Anhydride, to the
freshwater alga, Raphidocelis subcapitata, over a 72-hour exposure
The study was based on
procedures outlined in OECD Guidelines for Testing of Chemicals,
Guideline 201: Freshwater Alga and Cyanobacteria, Growth Inhibition
Test; and the Official Journal of the European Communities No. L383 A,
Method C.3.: Algal Inhibition Test.
The freshwater alga,
Raphidocelis subcapitata, was exposed to a series of five treatment
levels of Tetrabromophthalic Anhydride ranging from 2.5 to 41 mg/L,
based on mean measured concentrations. The toxicity of
Tetrabromophthalic Anhydride to Raphidocelis subcapitata was assessed
based on effects on cell density, growth rate, and yield relative to the
The 72-hour NOEC was
determined to be 41 mg/L based on a lack of statistically significant
reductions in cell density, growth rate, and yield in any of the
treatment groups. The 72-hour EC10 values for cell density, growth rate,
and yield were determined to be 32, >41, and 32 mg/L, respectively. The
72-hour EC50 values for cell density, growth rate, and yield were
determined to be >41 mg/L, for all three endpoints.
72-hour NOEC (cell density,
growth rate and yield): 41 mg/L.
72-hour EC50 (cell density,
growth rate, and yield) : >41 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Ce site web utilise des cookies afin de vous garantir la meilleure expérience possible sur nos sites web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again