Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 206-114-9 | CAS number: 302-01-2
Respiratory sensitisation
Administrative data
- Endpoint:
- respiratory sensitisation
- Remarks:
- other: reviewed data
- Type of information:
- other: Summary evaluation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: summarized by SCOEL
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- SCOEL/REC/164 - Hydrazine - Recommentation from the Scientific Committee on occupational exposure limits
- Author:
- SCOEL (Scientific Committee on Occupational Exposure Levels)
- Year:
- 2 016
- Bibliographic source:
- SCOEL (Scientific Committee on Occupational Exposure Levels)
- Report date:
- 2016
- Reference Type:
- publication
- Title:
- Reactive airways dysfunction syndrone (RADS): Persistent asthma syndrome after high level irritant exposure
- Author:
- Brooks SM, Weiss MA, Bernstein IL,
- Year:
- 1 985
- Bibliographic source:
- Chest 88, 376-384 cited in SCOEL 2009
- Reference Type:
- publication
- Title:
- Toxicity assessment of hydrazine fuels
- Author:
- Keller WC
- Year:
- 1 988
- Bibliographic source:
- Aviat Spyce Environm Med 59, 100-106 cited in SCOEL 2009
- Reference Type:
- review article or handbook
- Title:
- Other chemical substances causing occupational asthma in : Bernstein IL, Chan-yeung M. Malo JL, Bernstein DI (eds) Asthma in the workplace
- Author:
- Malo JL, Bernstein IL
- Year:
- 1 993
- Bibliographic source:
- marcel Dekker , New York, Basel, Hong Kong, 481-502 cited in SCOEL 2009
- Reference Type:
- publication
- Title:
- Long-term inhalation toxicity of hydrazine
- Author:
- Vernot EH, MacEwan JD, Brunner RH, Haun CC, Kinkead ER, Prentice DE, Hall A, Schmidt RE, Eason RL, Hubbard GB, Young JT
- Year:
- 1 985
- Bibliographic source:
- Fundam Appl Toxicol 5, 1050-1064 cited in SCOEL 2009
Materials and methods
- Principles of method if other than guideline:
- Reviewed data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Hydrazine
- EC Number:
- 206-114-9
- EC Name:
- Hydrazine
- Cas Number:
- 302-01-2
- Molecular formula:
- H4N2
- IUPAC Name:
- hydrazine
- Details on test material:
- reviewed data
Constituent 1
Test animals
- Species:
- other: reviewed data
- Strain:
- other: reviewed data
- Details on test animals or test system and environmental conditions:
- reviewed data
Test system
- Route of induction exposure:
- other: reviewed data
- Route of challenge exposure:
- other: reviewed data
- Vehicle:
- other: reviewed data
- Concentration:
- reviewed data
- No. of animals per dose:
- reviewed data
Results and discussion
- Results:
- Despite numerous descriptions of irritative reactions of the respiratory passages to hydrazine in the literature, there is no evidence that hydrazine causes allergic reactions in the respiratory tract. Specific animal experiments are not available.
Any other information on results incl. tables
Despite numerous descriptions of irritative reactions of the respiratory passages to hydrazine in the literature, there is no evidence that hydrazine causes allergic reactions in the respiratory tract. Specific animal experiments are not available.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
