Registration Dossier
Registration Dossier
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EC number: 200-467-2 | CAS number: 60-29-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original study not available. Based on IUCLID data summary.
Data source
Reference
- Reference Type:
- publication
- Title:
- Acute inhalation toxicity of volatile hydrocarbons
- Author:
- Swann, H.E., Kwon, B.K., Hogan, G.K., Snellings, W.M.
- Year:
- 1 974
- Bibliographic source:
- Am. Ind. Hyg. Assoc. J., 1974, 35, 511-518
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: no information available
- Principles of method if other than guideline:
- No information on the method or guideline used was available.
- GLP compliance:
- no
- Test type:
- other: no available information
- Limit test:
- no
Test material
- Reference substance name:
- Diethyl ether
- EC Number:
- 200-467-2
- EC Name:
- Diethyl ether
- Cas Number:
- 60-29-7
- Molecular formula:
- C4H10O
- IUPAC Name:
- diethyl ether
- Details on test material:
- No information on the test material used is available.
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation: vapour
- Type of inhalation exposure:
- not specified
- Vehicle:
- other: no data
- Analytical verification of test atmosphere concentrations:
- not specified
- Remarks on duration:
- no information
- Concentrations:
- No information available.
- No. of animals per sex per dose:
- No information available. Total of four animals reported.
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LCLo
- Effect level:
- 397 mg/L air (nominal)
- Clinical signs:
- other: 99.2mg/L displayed slight excitation 198mg/L displayed deep anesthesia 397mg/L irregular respiration and respiratory arrest
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
