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EC number: 290-754-9
CAS number: 90218-76-1
The acute toxicity of 1,2,4-Benzenetricarboxylic acid,
mixed decyl and octyl triesters was investigated following dermal
administration of a single dose to the rat at 2000 mg/kg according to
OECD guideline 402, adopted on 24 February 1987 and Test method B.3
"Acute Toxicity (dermal)" described in Council Regulation (EC) No.
A single dose of 2000 mg/kg was administered to a group o
5 male and 5 female animals for 24 hours. After 14 days all animals were
killed and subjected to necropsy examination. No mortality occurred
following dosing and no signs of toxicity were observed. The body weight
changes observed during the study were within the expected range for
this species and age of animals. No significant abnormalities were found
at necropsy in the animals at termination of the study. No abnormalities
were observed at the treated site.
These results indicated that the test item has no toxic
effect on the rat following dermal exposure over a 24 hour period at a
level of 2000 mg/kg.
The lack of mortality demonstrated the LD50 to be greater
than 2000 mg/kg.
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