Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 270-877-4
CAS number: 68479-98-1
Oral: LD50 rat = 738 mg/kg bwDermal: LD50 rat/rabbit > 2000 mg/kg bwInhalation: DNEL (inhalation, short-term, systemic effects) = 0.0518 mg/m3
oral LD50 study in the rat demonstrated that the test material was
moderately toxic (LD50 = 738 mg/kg) when administered via the oral route
(Jones 1983). The LD50 was >2000 when applied to rats or rabbits via the
dermal route, indicating the test material has dermal toxicity (Allen
1993; Nelson et al., 1977). An acute inhalation study is not warranted
because an acute inhalation DNEL may be derived from the chronic oral
toxicity study by Ciafalo (1992).
The GHS criteria for classifying a substance as Category
4 acute toxicity hazard is triggered when the acute toxicity estimate is
between 300 and 2000 mg/kg body weight. Since the LD50 is 738 mg/kg body
weight, the test material is within range for classification as a
Category 4 acute toxicity hazard. See: Regulation (EC) No 1272/2008; See
Official Journal of the European Union, (2008) Vol. L353, pp. 1-1355, at
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again