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EC number: 270-877-4
CAS number: 68479-98-1
pharmacokinetic studies were performed in the rat (Hainje and El-hawari,
1982; Babin 1996). Both studies demonstrated that the test material was
absorbed via the oral route and distributed throughout the body. The
highest levels of the radioactivity were found in the pancreas, thyroid,
and liver. Urinary excretion was the primary route of elimination up to
24 hours, with fecal elimination occuring to a lesser
extent. Approximately 50 to >60% of the test material was eliminated
during the first 24 hours. Metabolites were evaluated at 24 hours and
suggested active phase I and phase II metabolism with approximately
44.2% of the radiolabel contained in the water soluble fraction (not
acid labile), 37.6% of the label consisted of acid-labile conjugates,
and approximately 18.2% of the label was contained in the organic
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