Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 220-479-1 | CAS number: 2781-00-2
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Short description of key information on bioaccumulation potential result:
No substance specific data on metabolism and kinetics are available. Based on physical-chemical characteristics, no or only limited absorption by the dermal and inhalation routes is expected, whereas oral absorption is more likely.
Key value for chemical safety assessment
- Bioaccumulation potential:
- high bioaccumulation potential
Additional information
No substance specific data on metabolism and kinetics are available, neither in human nor in animal.
Based on physical-chemical characteristics, particularly low water solubility (<0.62 mg/l), octanol-water partition coefficient (experimental log Kow is > 5.5, calculated log Kow :7.3) and low vapour pressure ( 9 x 10-7 mbars at 20°C), no or only limited absorption by the dermal and inhalation routes is expected, which is further supported by the acute dermal toxicity study results. Moreover the substance is not a skin irritant; therefore no increase of skin absorption is expected.
Based on this log Pow a logBCF was calculated: 3.96 (EPIWIN)
Based on the high log Kow and the very low water solubility, the substance can be regarded as a lipophilic substance. Such a lipophilic compound may be taken up by micellular solubilisation by oral route exposure. Inhalation is not likely since the substance is a powder, and with regards to granulometry.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
