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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Remarks:
GLP Study.
Qualifier:
no guideline available
Principles of method if other than guideline:
A laser beam passes through a continuous stream of particles. Each particle (sphere) produces a symmetrical pattern of scattered light intensity (‘flux pattern'), which is characteristic for its size, on a detector. From the superposed flux patterns of a large number of particles the particle size distribution (equivalent diameter) can be computed by means of an optical model, e.g. the Fraunhofer approximation.
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Key result
Percentile:
D50
Mean:
282 µm
Remarks on result:
other: No data on St. dev.
Key result
Percentile:
D10
Mean:
105 µm
Remarks on result:
other: No data on St. dev.
Key result
Percentile:
D90
Mean:
507 µm
Remarks on result:
other: No data on St. dev.

The measurements were performed three times. The results, expressed as volume distribution, are shown in the following tables:

Result

d10 (μm)

d50 (μm)

d90 (μm)

Sample 1

126.8

300.7

533.7

Sample 2

95.5

271.6

494.6

Sample 3

92.1

274.4

493.2

Average

104.8

282.2

507.2

Conclusions:
The average of three measurements is:
d10: 20.2 μm
d50: 61.7 μm
d90: 130.6 μm
Executive summary:

The particle size distribution (volume distribution) of the test item was measured by laser diffraction with dry dispersing.

The average of three measurements is:

d10: 20.2 μm

d50: 61.7 μm

d90: 130.6 μm

Description of key information

Key study. No guideline available. GLP study. The particle size distribution (volume distribution) of the test item was measured by laser diffraction with dry dispersing. The average of three measurements was:

d10: 20.2 μm

d50: 61.7 μm

d90: 130.6 μm

Additional information