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Hydrolysis:

Half life of hydrolysis of test chemical N-(4-{bis[4-(dimethylamino)phenyl]methylene}cyclohexa-2,5-dien-1-ylidene)-N-methylmethanaminium chloride ( CAS no. 548 -62 -9) is predicted using OECD QSAR tool box v.3.3 using log kow as primary descriptor. The half life of Hydrolysis of chemical N-(4-{bis[4-(dimethylamino)phenyl]methylene}cyclohexa-2,5-dien-1-ylidene)-N-methylmethanaminium chloride estimated  was 291.447 days at 50 deg. C. By this value it is concluded that this test chemical is expected to show negligible hydrolysis.

Additional information

Hydrolysis:

Predicted data for target compound N-(4-{bis[4-(dimethylamino)phenyl]methylene}cyclohexa-2,5-dien-1-ylidene)-N-methylmethanaminium chloride( CAS no.548 -62 -9) from OECD QSAR tool box.v.3.3 and supporting study for its read across chemical were reviewed as follow.

 

Half life of hydrolysis of test chemical N-(4-{bis[4-(dimethylamino)phenyl]methylene}cyclohexa-2,5-dien-1-ylidene)-N-methylmethanaminium chloride ( CAS no. 548 -62 -9) is predicted using OECD QSAR tool box v.3.3 using log kow as primary descriptor. The half life of Hydrolysis of chemical N-(4-{bis[4-(dimethylamino)phenyl]methylene}cyclohexa-2,5-dien-1-ylidene)-N-methylmethanaminium chloride estimated  was 291.447 days at 50 deg. C. By this value it is concluded that this test chemical is expected to show negligible hydrolysis.

 

In a supporting study from authoritative database ( Comptox chemistry Dashboard, 2017) the hydrolysis rate constant of read across chemical 4-[(4-dimethylaminophenyl)-phenylmethylidene]cyclohexa-2,5-dien-1-ylidene]-dimethylazanium chloride estimated is 4.31e-11 cm3/mol/sec as this hydrolysis rate constant is very less this chemical shows negligible hydrolysis and it is also supported by data obtained from authoritative database ( HSDB) that this chemical lack hydrolyzable functional group and does not undergo hydrolysis.

 

By considering results of both studies it is concluded that the target chemical N-(4-{bis[4-(dimethylamino)phenyl]methylene}cyclohexa-2,5-dien-1-ylidene)-N-methylmethanaminium chloride is shows negligible hydrolysis..