Registration Dossier
Registration Dossier
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EC number: 939-401-9 | CAS number: 1469983-41-2
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
An acute study in earthworm with the source substance showed that the 14-d LC50 is >1000 mg/kg dw. No mortality was observed in either control or test group. No significant effect was observed with regard to the weight of the worms.
Key value for chemical safety assessment
Additional information
Executive summary of the study performed with the source substance:
A study was performed to assess the acute toxicity of the test material to the earthworm (Eisenia foetida) in an artificial soil. The method followed that described in the OECD Guidelines for Testing of Chemicals (1984) No 207 "Earthworm, Acute Toxicity Tests" and EEC Commission Directive 87/302/EEC. Following a preliminary range-finding study, 60 earthworms (six replicates of 10 worms) were exposed to a single concentration of 1000 mg/kg of soil for a period of 14 days. The number of mortalities were determined after 7 and 14 days exposure. A positive control study using chloroacetamide, conducted approximately every 6 months, was reported for reference purposes. The 14-Day LC50 for the test material to earthworms (Eisenia foetida) based on nominal test concentrations was greater than 1000 mg/kg: The No Observed Effect Concentration was >= 1000 mg/kg. The result of the positive control study gave a 14-Day LC50 for chloroacetamide of 23 mg/kg with 95% confidence limits of 20 - 25 mg/kg.
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