Registration Dossier
Registration Dossier
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EC number: 229-563-2 | CAS number: 6610-29-3
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The Log Kow for 4-methylthiosemicarbazide is calculated to be -1.21.Considering this value,4-methylthiosemicarbazide has a low potential for bioaccumulation.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -1.21
Additional information
The Log Kow for 4-methylthiosemicarbazide is calculated to be -1.21.Considering this value,4-methylthiosemicarbazide has a low potential for bioaccumulation.
According to the Guidance on information requirements and chemical safety assessment Chapter R.7a: Endpoint specific guidance (ECHA, 2008), the impact of errors on model predictions for a log Kow value below 1 is usually less critical. Moreover, the value estimated is outside the applicability range of the reverse phase HPLC method (OECD GL 117) and very closed to the lowest value of the applicability range of the shake flask method (OECD GL 107). Therefore, it is considered that an experimental study is not needed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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