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EC number: 221-717-7 | CAS number: 3209-22-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- measured log Pow , no further information
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Partition coefficient type:
- octanol-water
- Analytical method:
- other: no data
- Type:
- log Pow
- Partition coefficient:
- 3.05
- Remarks on result:
- other: The pH-value and the temperature were not reported.
- Conclusions:
- Partition coefficient of 1,2-dichloro-3-nitrobenzene is given as log Pow = 3.05
The pH-value and the temperature were not reported - Executive summary:
Cronin, 2001
Partition coefficiet of 1,2-dichloro-3-nitrobenzene: log Pow = 3.05
The pH-value and the temperature were not reported.
- Endpoint:
- partition coefficient
- Type of information:
- not specified
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Partition coefficient type:
- octanol-water
- Analytical method:
- other:
- Type:
- log Pow
- Partition coefficient:
- 3.05
- Remarks on result:
- other: The pH-value and the temperature were not reported.
- Details on results:
- The pH-value and the temperature were not reported.
- Conclusions:
- The partition coefficiet of 1,2-dichloro-3-nitrobenzene is log Pow = 3.05
The pH-value and the temperature were not reported. - Executive summary:
National Institute for Occupational Safety and Health; online, 2009
Partition coefficiet of 1,2-dichloro-3-nitrobenzene: log Pow = 3.05
The pH-value and the temperature were not reported.
- Endpoint:
- partition coefficient
- Type of information:
- other: BUA-report
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Remarks:
- No reliability is given as this is a summary entry for the BUA-report.
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- BUA-report
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Partition coefficient type:
- octanol-water
- Analytical method:
- other:
- Type:
- log Pow
- Partition coefficient:
- 3.01
- Remarks on result:
- other: The pH-value and the temperature were not reported.
- Type:
- log Pow
- Partition coefficient:
- 3.08
- Remarks on result:
- other: The pH-value and the temperature were not reported.
- Type:
- log Pow
- Partition coefficient:
- 3.05
- Remarks on result:
- other: The pH-value and the temperature were not reported.
- Type:
- log Pow
- Partition coefficient:
- 2.9
- Remarks on result:
- other: The pH-value and the temperature were not reported.
- Conclusions:
- The data on log Kow range from 2.9 (Canton et al., 1985) to 3.08 (McCrady et al., 1987).
- Executive summary:
BUA-report
The data on log Kow range from 2.9 (Canton et al., 1985) to 3.08 (McCrady et al., 1987).
The log Kow, studied using the shake flask method, was observed to be 2.9 (Canton et al., 1985), 3.05 (Kaiser, 1983; Kaiser& Ribo, 1985), 3.08 (McCrady et al, 1987). Deneer at al., 1987 measured a log Kow = 3.01 using reverse phase HPLC.
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Partition coefficient type:
- octanol-water
- Analytical method:
- other:
- Type:
- log Pow
- Partition coefficient:
- 3.05
- Remarks on result:
- other: The pH-value and the temperature were not reported.
- Details on results:
- The pH-value and the temperature were not reported.
- Conclusions:
- Partition coefficiet of 1,2-dichloro-3-nitrobenzene is determined as log Pow = 3.05 by shake flask method. The pH-value and the temperature were not reported
- Executive summary:
HSDB 2009
Partition coefficiet of 1,2-dichloro-3-nitrobenzene: log Pow = 3.05
The pH-value and the temperature were not reported.
Referenceopen allclose all
The pH-value and the temperature were not reported.
BUA-report
The data on log Kow range from 2.9 (Canton et al., 1985) to 3.08 (McCrady et al., 1987).
The log Kow, studied using the shake flask method, was observed to be 2.9 (Canton et al., 1985), 3.05 (Kaiser, 1983; Kaiser& Ribo, 1985), 3.08 (McCrady et al, 1987). Deneer at al., 1987 measured a log Kow = 3.01 using reverse phase HPLC.
The pH-value and the temperature were not reported.
Description of key information
The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.
The partition coefficient of 1,2-dichloro-3-nitrobenzene was determined in a series of experimental studies and found to be in the range of 2.9 to 3.08:
HSDB 2009
Partition coefficiet of 1,2-dichloro-3-nitrobenzene: log Pow = 3.05
The pH-value and the temperature were not reported.
BUA-report
The data on log Kow range from 2.9 (Canton et al., 1985) to 3.08 (McCrady et al., 1987). The log Kow, studied using the shake flask method, was observed to be 2.9 (Canton et al., 1985), 3.05 (Kaiser, 1983; Kaiser& Ribo, 1985), 3.08 (McCrady et al, 1987). Deneer at al., 1987 measured a log Kow = 3.01 using reverse phase HPLC.
National Institute for Occupational Safety and Health; online, 2009
Partition coefficiet of 1,2-dichloro-3-nitrobenzene: log Pow = 3.05
The pH-value and the temperature were not reported.
Cronin, 2001
Partition coefficiet of 1,2-dichloro-3-nitrobenzene: log Pow = 3.05
The pH-value and the temperature were not reported.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 3.05
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.