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Diss Factsheets
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EC number: 219-674-4 | CAS number: 2495-37-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2000-05-04 to 2000-06-02
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- GLP.
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Version / remarks:
- adopted 31 July 1992
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- adopted 17 July 1992
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Benzyl methacrylate
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): water treatment plant Emeraude (SIARR) 76141 Petit-Quevilly, France; sampling date 26 April 2000
- Preparation of inoculum for exposure: initial sieving of sewage sludge, 5 min centrifugation, rejection of supernatant, redispersion of pellet in mineral medium
- Pretreatment: to wash out DOC, preconditioning for 6 days (air was bubbled through the inoculum during preconditioning), 22 ± 2°C
- Concentration of sludge: 12 mg/L (dry weight)
- Initial cell/biomass concentration: no data
- Water: reconstituted deionised water containing no more than 10% of the organic carbon introduced by addition of test substance / reference substance - Duration of test (contact time):
- 28 d
- Initial conc.:
- 10 mg/L
- Based on:
- other: TOC
- Initial conc.:
- 40 other: mg/flask (3 L)
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to OECD guideline 301
- Additional substrate: no
- Solubilising agent (type and concentration if used): none
- Test temperature: 20 - 23°C
- pH: at beginning of the test 7.58; day 28: 8.21 - 8.59
- pH adjusted: no
- Aeration of dilution water: flasks were bubbled with CO2-scrubbed air at 30 – 100 mL/min
- Suspended solids concentration: 12 mg/L
- Continuous darkness: yes (dark glass bottles fitted with dark glass stoppers)
- other: stirring with magnetic stirrer to homogenate the culture
TEST SYSTEM
- Culturing apparatus:
- Number of culture flasks/concentration: 2/ inoculum blank, 2/test substance, 1/reference substance
- Method used to create aerobic conditions: aeration (flasks were bubbled with CO2-scrubbed air at 30 – 100 mL/min)
- Details of trap for CO2: series of 3 wash bottles filled with 100 mL 0.0125 M barium hydroxide
SAMPLING
- Sampling frequency: days 1, 5, 8, 11, 14, 18, 21, 25, 29
- Sampling method: The CO2 produced by degradation was collected in a series of 3 wash bottles filled with 100 mL 0.0125 Ba(OH)2. The amount of CO2 was calculated by titration of the Ba(OH)2 solution with 0.05 M HCl, using phenolphthalein as indicator.
- Sterility check if applicable: no
- Sample storage before analysis: no data, probably immediate analysis
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes (2 flasks)
- Abiotic sterile control: no
- Toxicity control: no
- Other: reference substance (sodium acetate) - Reference substance:
- acetic acid, sodium salt
- Remarks:
- 10 mg TOC/L
- Preliminary study:
- n/a
- Test performance:
- n/a
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 74
- Sampling time:
- 28 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 64
- Sampling time:
- 12 d
- Remarks on result:
- other: end of 10 day window
- Details on results:
- The 10-day window started on day 2. Biodegradation totalled 64% at the end of the 10 day window (day 12) and 74% at the end of the test period.
- Results with reference substance:
- The reference substance degraded normally under the test conditions (68% after 14 days).
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The ready biodegradation of BNMA was investigated in a CO2 evolution test over a period of 28 days and using domestic sewage as inoculum. Inoculum blank and procedural/functional control with the reference substance sodium acetate were performed.
The 10-day window started on day 2. Biodegradation totalled 64% at the end of the 10 day window (day 12) and 74% at the end of the test period. The test item proved to be readily biodegradable and fulfilling the 10-d window criterion. - Executive summary:
The ready biodegradation of BNMA was investigated in a study conducted according to OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test) adopted 17 July 1992 and EU Method C.4-C, 31 July 1992, over a period of 28 days using sewage sludge sampled from the aeration tank of a predominantly domestic sewage treatment plant as inoculum. The biodegradation rate was determined by measurement of CO2 evolution. Inoculum blank and procedural/functional control with the reference substance sodium acetate were performed.
After 28 days the degradation of BNMA reached 74%.The functional control reached the pass level >60% after 14 d.
This study is regarded as reliable without restriction and satisfies the guideline requirements for ready biodegradation. BNMA proved to be readily biodegradable and fulfilling the 10-d window criterion.
NOTE: Any of data in this dataset are disseminated by the European Union on a right-to-know basis and this is not a publication in the same sense as a book or an article in a journal. The right of ownership in any part of this information is reserved by the data owner(s). The use of this information for any other, e.g. commercial purpose is strictly reserved to the data owners and those persons or legal entities having paid the respective access fee for the intended purpose.
Reference
Description of key information
BNMA proved to be readily biodegradable and fulfilling the 10-d window criterion.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
One study on biodegradation of BNMA is available, which is considered as reliable without restrictions (Klimisch score 1):
The ready biodegradation of BNMA was investigated in a study conducted according to OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test) adopted 17 July 1992 and EU Method C.4-C, 31 July 1992, over a period of 28 days using sewage sludge sampled from the aeration tank of a predominantly domestic sewage treatment plant as inoculum. The biodegradation rate was determined by measurement of CO2 evolution. Inoculum blank and procedural/functional control with the reference substance sodium acetate were performed.
After 28 days the degradation of BNMA reached 74%. The functional control reached the pass level >60% after 14 d. BNMA proved to be readily biodegradable and fulfilling the 10-d window criterion.
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