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EC number: 217-421-2 | CAS number: 1843-05-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to daphnids, no toxic effects occur within the range of water solubility.
Key value for chemical safety assessment
Additional information
The toxicity to aquatic invertebrates of the test substance was tested in a semi-static GLP guideline study according to the “Method of test concerning new chemical substance <Alga growth inhibition test, Daphnia acute immobilization test, and fish acute toxicity test>” (Notification No. 1121002 of the Pharmaceutical and Food Safety Bureau, Ministry of Health, Labour and Welfare, dated November 13, 2003, (Heisei 15-11-13), No. 2 of the Manufacturing Industries Bureau, Ministry of Economy, Trade and Industry, and Notification No. 031121002 of the Environmental Policy Bureau, Ministry of the Environment, dated November 21, 2003)". After 48 h no acute toxicity within the range of solubility could be observed. The water solubility was tested in a preliminary study to guarantee that the main test will be conducted up to the maximum solubility within the test media. Therefore, DMF was additionally used as solubilizer and a limit test was conducted.
Since no acute toxic effects occurred within the range of solubility, the test substance is with high probability acutely not harmful to aquatic invertebrates
The results are supported by a second study: The EC50 value of the test substance in Daphnia magna was determined to be 52 mg/L in a study using an emulsifier due to the low water solubility of the test substance (CIBA-GEIGY 1988b). The water solubility of the test item was determined to be lower than 0.73 µg/L (Cytec 971/121, 2001). The EC0 value of 10 mg/L reported in the study on daphnids clearly shows that there were no acute toxic effects within the range of water solubility.
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