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Diss Factsheets

Physical & Chemical properties

Melting point / freezing point

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Administrative data

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Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
July 2015
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
HEXAMIDINE BATCH 40686
Key result
Melting / freezing pt.:
ca. 217 °C
Decomposition:
yes
Decomp. temp.:
> 292 °C

mass loss = 0.2mg

Conclusions:
Melting point by differential scanning calorimetry ca 217°C
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
capillary method
Specific details on test material used for the study:
Hexamidine diisethionate Batch 41519
white powder
purity 99.8%
Key result
Melting / freezing pt.:
> 213.7 - < 220.9 °C

at the end of the study the item is brown instead of white

Conclusions:
The melting point is between 213.7 and 220.9°C

Description of key information

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
217 °C

Additional information